About: Silicone rubber is a(n) research topic. Over the lifetime, 16569 publication(s) have been published within this topic receiving 132667 citation(s). The topic is also known as: silicone elastomer & silicone elastomers.
TL;DR: When tissue cells are cultured on very thin sheets of cross-linked silicone fluid, the traction forces the cells exert are made visible as elastic distortion and wrinkling of this substratum.
Abstract: When tissue cells are cultured on very thin sheets of cross-linked silicone fluid, the traction forces the cells exert are made visible as elastic distortion and wrinkling of this substratum. Around explants this pattern of wrinkling closely resembles the "center effects" long observed in plasma clots and traditionally attributed to dehydration shrinkage.
Abstract: Polydimethylsiloxane (PDMS) is a commercially available physically and chemically stable silicone rubber. It has a unique flexibility with a shear elastic modulus due to one of the lowest glass transition temperatures of any polymer . Further properties of PDMS are a low change in the shear elastic modulus versus temperature , virtually no change in G versus frequency and a high compressibility. Because of its clean room processability, its low curing temperature, its high flexibility, the possibility to change its functional groups and the very low drift of its properties with time and temperature, PDMS is very well suited for micromachined mechanical and chemical sensors, such as accelerometers (as the spring material) and ISFETs (as the ion selective membrane). It can also be used as an adhesive in wafer bonding, as a cover material in tactile sensors and as the mechanical decoupling zone in sensor packagings.
TL;DR: A superhydrophobic fabric coating made of a crosslinked polydimethylsiloxane elastomer, containing well-dispersed hydrophobic silica nanoparticles and fluorinated alkyl silane shows remarkable durability against repeated machine washes, severe abrasion, strong acid or base, boiling water or beverages and excellent stain resistance.
Abstract: A superhydrophobic fabric coating made of a crosslinked polydimethylsiloxane elastomer, containing well-dispersed hydrophobic silica nanoparticles and fluorinated alkyl silane, shows remarkable durability against repeated machine washes, severe abrasion, strong acid or base, boiling water or beverages and excellent stain resistance.
TL;DR: The present study finds a "viscosity" that would maintain the "clarity" of the vitreous of rabbits and help in "replacing the retina" in plastic surgery and retinal detachment procedures.
Abstract: Introduction Silicone rubber has been widely used as implant material in plastic surgery and in retinal detachment procedures. 1 Liquid silicone was first injected into the vitreous cavity of rabbits by Stone, 2 who reported that silicone fluids of various viscosities were well tolerated and produced "very little change in the rabbit eyes over a period of two years." He went on to predict that it might be possible to find a "viscosity" that would maintain the "clarity" of the vitreous and help in "replacing the retina." Recently, other investigators 3-5 have confirmed Stone's observations. However, their animal experiments emphasized the possibilities of complications. Everett 4 reported cataract formation following the injection of liquid silicone into the vitreous cavity of rabbits; Galavin 5 produced glaucoma by the injection of liquid silicone into the posterior chamber of the rabbit eye. The present study serves a dual purpose: (1) to report further
TL;DR: QAS-coated silicone rubber shows antimicrobial properties against adhering bacteria, both in vitro and in vivo.
Abstract: Biomaterial-centered infection is a dreaded complication associated with the use of biomedical implants. In this paper, the antimicrobial activity of silicone rubber with a covalently coupled 3-(trimethoxysilyl)-propyldimethyloctadecylammonium chloride (QAS) coating was studied in vitro and in vivo. Gram-positive Staphylococcus aureus ATCC 12600, Staphylococcus epidermidis HBH, 102, and Gram-negative Esherichia coli O2K2 and Pseudomonas aeruginos AK1 were seeded on silicone rubber with and without QAS-coating, in the absence or presence of adsorbed human plasma proteins. The viability of the adherent bacteria was determined using a live/dead fluorescent stain and a confocal laser scanning microscope. The coating reduced the viability of adherent staphylococci from 90% to 0%), and of Gram-negative bacteria from 90% to 25% while the presencc of adsorbed plasma proteins had little influence. The biomaterials were also subcutaneously implanted in rats for 3 or 7 days, while pre- or postoperatively seeded with S. aureus ATCC 12600. Preoperative seeding resulted in infection of 7 out of 8 silicone rubber implants against 1 out of 8 QAS-coated silicone rubber implants. Postoperative seeding resulted in similar infection incidences on both implant types, but the numbers of adhering bacteria were 70% lower on QAS-coated silicone rubber. In conclusion, QAS-coated silicone rubber shows antimicrobial properties against adhering bacteria, both in vitro and in vivo.