Topic
Sleep disorder
About: Sleep disorder is a research topic. Over the lifetime, 19380 publications have been published within this topic receiving 884281 citations. The topic is also known as: somnipathy & non-organic sleep disorder.
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TL;DR: Sleep disturbance may be more prevalent among smokers due to the stimulant effects of nicotine, nightly withdrawal, an increased prevalence of sleep disordered breathing relative to nonsmokers, and/or an association with psychological disturbance.
285 citations
TL;DR: In the only clinical trials that investigated the use of a hypnosedative drug in an 'as-needed' regimen, zolpidem produced a global improvement in sleep and remains a useful therapeutic option in the pharmacological treatment of patients with insomnia.
Abstract: Zolpidem (Ambien, Stilnox, Myslee, an imidazopyridine, is a nonbenzodiazepine hypnotic indicated for the short-term treatment of insomnia. Zolpidem improves sleep in patients with insomnia. Its overall tolerability is favourable when administered according to the manufacturer's prescribing information, with a low propensity to cause clinical residual effects, withdrawal, dependence or tolerance. In addition, most evidence suggests that the drug is associated with minimal rebound insomnia. In the only clinical trials that investigated the use of a hypnosedative drug in an 'as-needed' regimen, zolpidem produced a global improvement in sleep. Thus, zolpidem continues to be a useful therapeutic option in the pharmacological treatment of patients with insomnia.
284 citations
TL;DR: Empirical and pathophysiological studies indicate that there may be a causal link between primary sleep abnormalities and cardiovascular and metabolic disease, such as hypertension, atherosclerosis, stroke, heart failure, cardiac arrhythmias, sudden death, obesity, and the metabolic syndrome.
284 citations
TL;DR: The National Sleep Foundation Web site is a comprehensive source of timely, authoritative information about sleep, specific sleep problems and disorders, and the issues associated with them.
Abstract: The National Sleep Foundation (NSF) Web site is a comprehensive source of timely, authoritative information about sleep, specific sleep problems and disorders, and the issues associated with them. In Spanish and English, with resources for health consumers and health care professionals, this Web site meets a broad range of information needs.
283 citations
TL;DR: The causes of insomnia in the elderly, the approach to patient evaluation, and the nonpharmacologic and pharmacologic treatment of insomnia are reviewed.
283 citations