Sleep disorder

About: Sleep disorder is a research topic. Over the lifetime, 19380 publications have been published within this topic receiving 884281 citations. The topic is also known as: somnipathy & non-organic sleep disorder.

Sleep Disorders Medicine: Basic Science, Technical Considerations, and Clinical Aspects

Abstract: Part I Basic aspects of sleep: an overview of sleep neurophysiology of sleep biochemical pharmacology of sleep physiological changes during sleep. Part 2 Technical considerations: polysomnographic technique EEG, EMG and EOG EKG recognition of cardiac arrhythmias respiration and respiratory function - technique of recording and evaluation measurement of sleepiness/alertness - MSLT ambulatory cassette polysomnography sleep scoring technique techniques for the evaluation of sleep-related erections. Part 3 Clinical aspects: an approach to a patient with sleep complaints classification of sleep disorders sleep apnea syndromes insomnia narcolepsy motor functions and dysfunctions of sleep sleep, breathing, and neurological disorders sleep disorders in psychiatric illness sleep and other medical disorders circadian rhythm disorders parasomnias sleep disorders in the elderly sleep disorders in childhood sleep and epilepsy positive airway pressure in the treatment of sleep related breathing disorders.

Variation of C-reactive protein levels in adolescents: association with sleep-disordered breathing and sleep duration.

Abstract: Background— There is increasing evidence that sleep-disordered breathing (SDB) is an independent risk factor for cardiovascular disease (CVD) in adults. C-reactive protein (CRP), a marker of systemic inflammation, is an important predictor of future cardiovascular events. The goal of this study was to quantify the associations of SDB, sleep duration, and CRP in adolescents to better understand the role of SDB in CVD risk. Methods and Results— Adolescents (n=143; age, 13 to 18 years; 36% black; 50% female) with a wide range of SDB severity underwent polysomnography and measurement of high-sensitivity CRP. SDB was quantified with the apnea hypopnea index (AHI) and oxygen desaturation measures. Sleep duration was estimated from 7-day actigraphy. The independent and dose-response associations of SDB with CRP were addressed through linear mixed-effects models. Forty-eight percent were overweight or obese, and 12% had SDB (AHI ≥5). CRP levels varied with increasing body mass index and SDB. After adjustment for ...

Polysomnographic diagnosis of idiopathic REM sleep behavior disorder.

Abstract: The presence of either excessive tonic chin EMG activity during REM sleep, or excessive phasic submental or limb EMG twitching is required to diagnose REM sleep behavior disorder (RBD). The aim was to identify cut-off values and to assess the sensitivity and specificity of these values taken separately or combined to diagnose idiopathic RBD patients. Eighty patients presenting with a clinical diagnosis of idiopathic RBD and 80 age- and gender-matched normal controls were studied in the sleep laboratory. Receiver operating characteristic curves were drawn to find optimal cut-off values for three REM sleep EMG parameters. Tonic and phasic EMG activity were measured in the chin, but not in the limbs. Videos were examined during the recording but were not systematically reviewed by the authors. Total correct classification of 81.9% was found for tonic chin EMG density ≥30%; 83.8% for phasic chin EMG density ≥15% and 75.6% for ≥24 leg movements per hour of REM sleep. Five patients did not fulfill any of these three polysomnographic (PSG) criteria. Conversely, one subject of the control group met the PSG criteria for RBD. This study estimates the diagnostic value of a visual scoring method for the diagnosis of idiopathic RBD and establishes cut-off values to be used in clinical and research set-ups. For the five RBD patients who did not show chin EMG abnormalities, it cannot be excluded that they had increased phasic EMG activity in the upper limbs and presented visible motor activity.