Slow-wave sleep

About: Slow-wave sleep is a research topic. Over the lifetime, 6543 publications have been published within this topic receiving 320663 citations. The topic is also known as: deep sleep.

Using DTX and DRX in a wireless communication system

Abstract: Systems, methodologies, and devices are described that can facilitate reducing power consumption associated with mobile devices. A mobile device can utilize a sleep mode controller that can facilitate selecting and/or switching to a desired sleep mode based in part on predefined sleep mode criteria. The sleep modes can include a non-sleep mode, light sleep mode, and/or deep sleep mode. The mobile device can employ an analyzer to evaluate information related to explicit signals, implicit signals, and/or the current sleep mode to determine whether a condition is met based in part on the predefined sleep mode criteria such that a transition to a different sleep mode is to be performed. If such a condition is met, the sleep mode controller can facilitate transitioning from the current sleep mode to a different sleep mode to facilitate reducing power consumption by the mobile device.

Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep

Abstract: Astrocytic Ca2+ signaling has been intensively studied in health and disease but has not been quantified during natural sleep. Here, we employ an activity-based algorithm to assess astrocytic Ca2+ signals in the neocortex of awake and naturally sleeping mice while monitoring neuronal Ca2+ activity, brain rhythms and behavior. We show that astrocytic Ca2+ signals exhibit distinct features across the sleep-wake cycle and are reduced during sleep compared to wakefulness. Moreover, an increase in astrocytic Ca2+ signaling precedes transitions from slow wave sleep to wakefulness, with a peak upon awakening exceeding the levels during whisking and locomotion. Finally, genetic ablation of an important astrocytic Ca2+ signaling pathway impairs slow wave sleep and results in an increased number of microarousals, abnormal brain rhythms, and an increased frequency of slow wave sleep state transitions and sleep spindles. Our findings demonstrate an essential role for astrocytic Ca2+ signaling in regulating slow wave sleep.

The alerting effects of naps in sleep-deprived subjects.

Abstract: The effect of napping for varying durations after one night of sleep deprivation was examined. Sleep latency tests were used to determine levels of sleepiness/alertness at 2, 4, 6, and 8 hrs following a morning nap of 0, 15, 30, 60, or 120 min duration. Ten normal-sleeping, young adult volunteers spent two consecutive days and the intervening night in the sleep laboratory on each of five weeks. Baseline sleep latencies were recorded the first day, sleep was deprived that night, a nap was taken at 0900 hrs, and sleep latencies were again recorded on the second day. The naps had differential alerting effects related to their duration, but none of the naps returned mean sleep latency for the 8 hrs to its basal levels. Alertness increased with nap duration, reaching its highest level with a 60-min nap; the 120-min nap was no more alerting than the 60-min nap. During the second hour of the 120-min nap, sleep became more fragmented with more shifts to stage 1 sleep or wake. Increased alertness was not strongly related to the sleep stage composition of the naps, the best predictor being minutes of slow wave sleep. Increased alertness was not detected until the second latency test 4 hrs after napping.

The effect of combined therapy (ultrasound and interferential current) on pain and sleep in fibromyalgia

Abstract: Multidisciplinary treatment has proven to be the best therapeutic option to fibromyalgia (FM) and physiotherapy has an important role in this approach Considering the controversial results of electrotherapy in this condition, the aim of this study was to assess the effects of combined therapy with pulsed ultrasound and interferential current (CTPI) on pain and sleep in FM Seventeen patients fulfilling FM criteria were divided into two groups, CTPI and SHAM, and submitted to pain and sleep evaluations Pain was evaluated by body map (BM) of the painful areas; quantification of pain intensity by visual analog scale (VAS); tender point (TP) count and tenderness threshold (TT) Sleep was assessed by inventory and polysomnography (PSG) After 12 sessions of CTPI or SHAM procedure, patients were evaluated by the same initial protocol After treatment, CTPI group showed, before and after sleep, subjective improvement of pain in terms of number (BM) and intensity (VAS) of painful areas (P<0001, both); as well as objective improvement, with decrease in TP count and increase in TT (P<0001, both) Subjective sleep improvements observed after CTPI treatment included decrease in morning fatigue and in non-refreshing sleep complaint (P<0001, both) Objectively, PSG in this group showed decrease in sleep latency (P<0001) and in the percentage of stage 1 (P<0001), increase in the percentage of slow wave sleep (P<0001) and in sleep cycle count (P<0001) Decrease in arousal index (P<0001), number of sleep stage changes (P<005) and wake time after sleep onset (P<005), were also observed and no difference regarding pain or sleep parameters were verified after SHAM procedure This study shows that CTPI can be an effective therapeutic approach for pain and sleep manifestations in FM