Topic
Slow-wave sleep
About: Slow-wave sleep is a research topic. Over the lifetime, 6543 publications have been published within this topic receiving 320663 citations. The topic is also known as: deep sleep.
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TL;DR: The selective disappearance of slow sleep characterizing the agrypnia excitata syndrome, together with other clinical and experimental findings, suggests that sleep can be divided into three types.
93 citations
TL;DR: In untreated schizophrenia, psychotic decompensation is associated with profound insomnia, one of the prodromal symptoms associated with psychotic relapse, but side effects may include sedation or residual insomnia.
93 citations
TL;DR: The influence of behavioral state on the induction of long-term enhancement of hippocampal synapses was studied in chronically prepared animals and LTE was strongly suppressed during SWS, suggesting that hippocampal information storage may be inactivated at certain phases of the sleep cycle.
93 citations
TL;DR: Anecdotal reports of sleep disturbance during pregnancy are abundant, but objective measurement of sleep changes has so far produced conflicting results.
Abstract: Background Anecdotal reports of sleep disturbance during pregnancy are abundant; however, objective measurement of sleep changes has so far produced conflicting results. Aims To objectively measure sleep architecture and investigate subjective sleep quality in the first and third trimester of pregnancy, when compared to the nonpregnant state. Methods Twenty-seven women in the third trimester of pregnancy, 21 women in the first trimester of pregnancy and 24 nonpregnant control women underwent overnight polysomnography and completed questionnaires regarding sleep quality and mood. Results Women in the third trimester of pregnancy had poorer sleep efficiency, more awakenings, less stage 4 sleep, more stage 1 sleep and fewer minutes in rapid eye movement sleep when compared to the control group. Cortical arousals were seen more often during pregnancy, particularly in response to respiratory events and limb movements. Sleep during the first trimester was affected to a lesser extent, with more wake time after sleep onset and less stage 4 sleep when compared to the controls. Conclusions Sleep during pregnancy is compromised by higher amounts of wake and cortical arousals leading to sleep fragmentation, with greater amounts of light sleep and less deep sleep. Mood state did not have an effect on sleep. Given the impact of sleep on well-being, this study increases our understanding of the characteristics of sleep during pregnancy, to help recognise when severe sleep disruption may warrant referral to a specialist for appropriate diagnosis and treatment.
93 citations
TL;DR: Improved sleep quality was reflected in improved daytime psychomotor performance and alertness and imply that benzodiazepine use may be beneficial in patients with central sleep apnea.
Abstract: It was hypothesized that triazolam might decrease central apneas associated with arousal periods in patients with central sleep apnea by hastening the onset of consolidated sleep Five male patients, diagnosed as having central sleep apnea on a screening night, participated in a double-blind randomized crossover study of the effect of placebo, 0125 mg triazolam, and 025 mg triazolam on sleep, respiration, and daytime function Results indicated that the medication increased total sleep and decreased central apnea index and number of brief arousals Improved sleep quality was reflected in improved daytime psychomotor performance and alertness These data, if replicated, imply that benzodiazepine use may be beneficial in patients with central sleep apnea
93 citations