scispace - formally typeset
Search or ask a question
Topic

Slow-wave sleep

About: Slow-wave sleep is a research topic. Over the lifetime, 6543 publications have been published within this topic receiving 320663 citations. The topic is also known as: deep sleep.


Papers
More filters
Journal ArticleDOI
01 Dec 1993-Brain
TL;DR: The sleep/wake status of three patients with bilateral lesions involving the paramedian thalamic regions was investigated and subjects with such lesions do not present a 'hypersomnia' but a 'de-arousal' or 'subwakefulness' with inability to develop sleep outside the normal circadian boundaries for its appearance.
Abstract: SUMMARY The sleep/wake status of three patients with bilateral lesions involving the paramedian thalamic regions was investigated Long-term monitoring with infrared video camera and polygraphy were performed In spite of presenting a behavioural aspect of sleep with sleep posture, eyes closed and lack of activity for 15–17 h per day, these subjects did not develop the normal non-rapid eye movement (NREM) and rapid eye movement (REM) sleep states during the daytime The EEG indicated presence of a mixture of low amplitude, irregular, diffuse theta and alpha range frequencies during hours associated with this ‘sleep-like’ behaviour Multiple sleep latency tests performed some time after the acute insult gave varying results, but while stage 1 NREM sleep might have been noted for three to four epochs, other states of sleep never appeared Patients were apathetic and ‘drowsy’ but could develop sleep only during the normal circadian period for sleep, ie during the night Even several years later, in one of the subjects in whom follow-up recordings were obtained, apathetic behaviour and sleep ‘posturing’ were present during much of the day, even though the subject, if requested, could perform tasks adequately all day long Subjects with such lesions do not present a ‘hypersomnia’ but a ‘de-arousal’ or ‘subwakefulness’ with inability to develop sleep outside the normal circadian boundaries for its appearance However, these subjects, at least initially, also lacked full wakefulness They have a behavioural impairment with a compulsive sleep posture and are left in the transition between wakefulness and sleep

89 citations

Journal ArticleDOI
TL;DR: Preschool children's behavioral and physiological responses to separation were monitored before, during, and after their mothers' hospitalization for the birth of a sibling, which characterized the hospital period as one of agitation.
Abstract: Preschool children's behavioral and physiological responses to separation were monitored before, during, and after their mothers' hospitalization for the birth of a sibling. During these 3 periods, play sessions were videotaped simultaneous with activity level and heart rate monitoring, nighttime sleep was time-lapse videotaped, and the parents were administered questionnaires on changes in their child's behaviors. Increases in fantasy play across these periods were interpreted as active coping both with the stress of separation and the altered interactions following the arrival of a new sibling. Increases in negative affect, activity level, heart rate, night wakings, and crying characterized the hospital period as one of agitation. Longer periods of deep sleep at this stage were interpreted as conservation withdrawal. Following the mother's return, decreases were noted in positive affect, activity level, heart rate, and active sleep suggestive of depression. These changes are discussed in the context of parallel data on agitation/depression during young primate separations.

89 citations

Journal ArticleDOI
TL;DR: It is shown that sleepiness and sleep disturbance vary across patient subgroups and that sleep disturbance is related to, although unable to account, for the pathological sleepiness of narcolepsy.
Abstract: This report describes night-time sleep and daytime sleepiness in a large (N=530) sample of patients meeting the International Classification of Sleep Disorders criteria for diagnosis of narcolepsy. Sleep data were obtained from polysomnographic recordings on two consecutive nights. Sleepiness was assessed using the Multiple Sleep Latency Test, the Maintenance of Wakefulness Test and the Epworth Sleepiness Scale. Analysis revealed that sleep was mild to moderately disturbed on both recording nights. A first-night effect was suggested by decreased REM latency and increased percentage REM and slow-wave sleep on the second night. Sleepiness and sleep disturbance varied across patient subgroups created based on patient ethnicity and on the presence/absence of cataplexy, sleep apnoea, and periodic limb movements. Covariation of sleep and sleepiness measures across patients was significant but weak. Strong association was found between subgroup means of sleep and sleep disturbance measures. The findings reported here show that sleepiness and sleep disturbance vary across patient subgroups and that sleep disturbance is related to, although unable to account, for the pathological sleepiness of narcolepsy.

89 citations

Journal ArticleDOI
TL;DR: These results indicate that neurons whose perikarya and/or processes are located within the pontine gigantocellular tegmental field and which are not part of the noradrenaline locus coeruleus complex, are critical for paradoxical sleep.

89 citations

Journal ArticleDOI
TL;DR: Available evidence suggests that the associations between sleep characteristics and cardiovascular risk vary by risk factor, and it is time to conduct studies to determine antecedent and consequent relationships, and to expand risk factors to include markers of inflammation.

89 citations


Network Information
Related Topics (5)
Dopaminergic
29K papers, 1.4M citations
83% related
Dopamine
45.7K papers, 2.2M citations
82% related
Prefrontal cortex
24K papers, 1.9M citations
82% related
Hippocampal formation
30.6K papers, 1.7M citations
82% related
Hippocampus
34.9K papers, 1.9M citations
82% related
Performance
Metrics
No. of papers in the topic in previous years
YearPapers
202364
2022103
2021171
2020163
2019166
2018152