Topic
Sodium fluoride
About: Sodium fluoride is a research topic. Over the lifetime, 3933 publications have been published within this topic receiving 65241 citations. The topic is also known as: floridine & sodium monofluoride.
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TL;DR: After fluoride ingestion, the severity of the effect on behavior increased directly with plasma F levels and F concentrations in specific brain regions, considering that plasma levels in this rat model are similar to those reported in humans exposed to high levels of fluoride.
289 citations
TL;DR: It is proposed that ATP participates in an early phase of enzyme degradation, and was shown, in the case of tyrosine aminotransferase, to be rapidly reversible and exerted by a mechanism different from the inhibition of protein synthesis.
280 citations
277 citations
TL;DR: Sodium fluoride takes effect slowly but effectively in preserving glucose in blood for at least three days, and its use is unnecessary if the concentration of glucose is to be measured within the first hour after sampling.
Abstract: How effective is sodium fluoride as a preservative of blood glucose? We compared changes in glucose concentration in fluoride-treated blood specimens with those of heparin-treated specimens. The former declined rapidly during the first hour; thereafter the rate of decrease was slower, and after 4 h the glucose concentration in the blood samples remained stable for up to three days. In contrast, the glucose concentration in the heparin-containing samples declined continuously. During the first hour, however, the rates of decline in the two types of samples were similar. Evidently sodium fluoride takes effect slowly but effectively in preserving glucose in blood for at least three days. Its use, however, is unnecessary if the concentration of glucose is to be measured within the first hour after sampling.
270 citations
TL;DR: In this paper, the effect of variable levels of fluoride and calcium intake, accompanied by vitamin D, on osteoporosis in eleven patients treated for one year Bone biopsies indicated an increase in new bone formation in all patients receiving 45 mg of sodium fluoride per day, whereas 600 mg of calcium per day prevented both osteomalacia and any increase in bone resorption.
248 citations