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Sodium metavanadate

About: Sodium metavanadate is a research topic. Over the lifetime, 256 publications have been published within this topic receiving 2903 citations. The topic is also known as: NaVO3 & sodium vanadium oxide.


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Journal ArticleDOI
TL;DR: In cells, vanadium compounds activate numerous signaling pathways and transcription factors, including PI3K-PKB/Akt-mTOR, NF-κB, MEK1/2-ERK, that cause cell survival or increased expression and release of VEGF, and they lower blood glucose levels in animals and in clinical trials.
Abstract: Vanadium belongs to the group of transition metals and is present in the air and soil contaminants in large urban agglomerations due to combustion of fossil fuels. It forms numerous inorganic compounds (vanadyl sulfate, sodium metavanadate, sodium orthovanadate, vanadium pentoxide) as well as complexes with organic compounds (BMOV, BEOV, METVAN). Depending on the research model, vanadium compounds exhibit antitumor or carcinogenic properties. Vanadium compounds generate ROS as a result of Fenton's reaction or of the reaction with atmospheric oxygen. They inactivate the Cdc25B(2) phosphatase and lead to degradation of Cdc25C, which induces G(2)/M phase arrest. In cells, vanadium compounds activate numerous signaling pathways and transcription factors, including PI3K-PKB/Akt-mTOR, NF-κB, MEK1/2-ERK, that cause cell survival or increased expression and release of VEGF. Vanadium compounds inhibit p53-dependent apoptosis and promote entry into the S phase of cells containing functional p53 protein. In addition, vanadium compounds, in particular organic derivatives, have insulin-mimetic and antidiabetic properties. Vanadium compounds lower blood glucose levels in animals and in clinical trials. They also inhibit the activity of protein tyrosine phosphatase 1B. By activating the PI3K-PKB/Akt pathway, vanadium compaunds increase the cellular uptake of glucose by the GLUT4 transporter. The PKB/Akt pathway is also used to inactivate glycogen synthase kinase-3. The impact of vanadium compounds on inflammatory reactions has not been fully studied. Vanadium pentoxide causes expression of COX-2 and the release of proinflammatory cytokines in a human lung fibroblast model. Other vanadium compounds activate NF-κB in macrophages by activating IKKβ.

139 citations

Journal ArticleDOI
TL;DR: The clinical and physical signs appearing after the intoxication include irregular respiration, diarrhea, ataxia and paralysis of the hind legs, which suggests a quick elimination of vanadium.

120 citations

Journal ArticleDOI
TL;DR: In this article, a catalytic process for the efficient production of formic acid (FA) from common carbohydrates via VO2+ formed by dissolving sodium metavanadate in acidic water was reported.

100 citations

Journal ArticleDOI
TL;DR: In this article, degradation reactions of free-standing air plasma-sprayed (APS) yttria-stabilized zirconia (YSZ) in contact with vanadium pentoxide (V2O5), phosphorus pentoxide, and sodium sulfate (Na2SO4) were investigated at temperatures up to 1200°C.
Abstract: The presence of vanadium, phosphorus, and sodium impurities in petcoke and coal/petcoke blends used in integrated gasification combined cycle (IGCC) plants warrants a clear understanding of high-temperature material degradation for the development of fuel-flexible gas turbines. In this study, degradation reactions of free-standing air plasma-sprayed (APS) yttria-stabilized zirconia (YSZ) in contact with vanadium pentoxide (V2O5), phosphorus pentoxide (P2O5), and sodium sulfate (Na2SO4) were investigated at temperatures up to 1200°C. Phase transformations and microstructural development were examined using X-ray diffraction, scanning electron microscopy, and transmission electron microscopy. Molten V2O5 reacted with solid YSZ to form zirconium pyrovanadate (ZrV2O7) at temperatures below 747°C. However, at temperatures above 747°C, molten V2O5 reacted with YSZ to form yttrium vanadate (YVO4). The formation of YVO4 led to the depletion of the Y2O3 stabilizer and deleterious transformation to the monoclinic ZrO2 phase. In addition, studies on YSZ degradation by Na2SO4 and a Na2SO4+V2O5 mixture (50–50 mol%) showed that Na2SO4 itself had no effect on the degradation of YSZ. However, in the presence of V2O5 at high temperatures, Na2SO4 forms vanadate compounds having a lower melting point such as sodium metavanadate (610°C), which was found to degrade YSZ by the formation of YVO4 at a relatively lower temperature of 700°C. P2O5 was found to react with APS YSZ by the formation of zirconium pyrophosphate (ZrP2O7) at all the temperatures studied. At temperatures as low as 200°C and as high as 1200°C, molten P2O5 was observed to react with solid YSZ to yield ZrP2O7, which led to the depletion of ZrO2 in YSZ (i.e., enrichment of Y2O3 in t′-YSZ) that promoted the formation of the fluorite-cubic ZrO2 phase.

100 citations

Journal ArticleDOI
TL;DR: In this article, a comprehensive mechanistic-based kinetic study of the oxidative degradation of CO2 loaded MEA, with and without a corrosion inhibitor (NaVO3), was performed in a stainless steel rotary-type autoclave with MEA concentrations of 11.4 and 17.9 mol %, NaVO3 concentration of 0.1 mol % and O2 pressures of 250 and 350 kPa.
Abstract: A comprehensive mechanistic-based kinetic study of the oxidative degradation of CO2 loaded MEA, with and without a corrosion inhibitor (NaVO3), was performed in a stainless steel rotary-type autoclave with MEA concentrations of 11.4 and 17.9 mol %, NaVO3 concentration of 0.1 mol %, O2 pressures of 250 and 350 kPa, and CO2 loading ranging from 0 to 0.44 (mol of CO2)/(mol of MEA) at temperatures of 328−393 K (typical absorber and stripper temperatures). The results showed that the presence of NaVO3 and increases in MEA concentration, temperature, or O2 pressure resulted in an increase in the MEA degradation rate. In contrast, an increase in CO2 loading led to a decrease in the degradation rate. The general mechanistic rate model obtained to represent all the systems investigated was of the following form: − rMEA = {k11[MEA]a[O2]b}/{k2 + k3[O2]c + k5[CO2]e}. This rate model shows that, in a CO2 loaded system, the loaded CO2 acts as a degradation inhibitor. In addition, the order of reaction with respect to ...

91 citations

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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
20214
20206
20199
201813
201717
201615