scispace - formally typeset
Search or ask a question

Showing papers on "Sodium propionate published in 1994"


Journal ArticleDOI
TL;DR: In this article, the effects of easily biodegradable organic carbon substrate on denitrification reaction and overall nitrogen removal from domestic wastewater under a modified sequencing batch reactor (SBR) system were examined.

46 citations


Journal ArticleDOI
TL;DR: Investigation of the effects of propionate on carbohydrate metabolism in normal and streptozocin (STZ)-induced diabetic male Sprague-Dawley rats found it did not alter basal or insulin-stimulated HGP or the MCR in either nondiabetic or diabetic animals.
Abstract: Undigested carbohydrates and some dietary fibers are fermented in the large intestine to form short-chain fatty acids (SCFA), including acetate, propionate, and butyrate. It has been suggested that some of the beneficial effects of high-carbohydrate, high-fiber diets on carbohydrate and lipid metabolism are mediated by the metabolism of SCFA in the liver. Propionate has been shown in vitro to decrease glucose production in rat hepatocytes. The aim of the present study was to investigate the effects of propionate on carbohydrate metabolism in normal and streptozocin (STZ)-induced diabetic male Sprague-Dawley rats. Rats were fed a high-fat diet with or without sodium propionate supplementation (either 0.5% or 5% wt/wt) for 4 weeks. At the completion of the feeding period, body weight and liver glycogen concentrations were significantly decreased in STZ-diabetic rats and were unaffected by propionate supplementation. Although STZ-diabetic animals had elevated fasting plasma glucose, cholesterol, and triglyceride levels relative to nondiabetic rats, propionate supplementation had no significant effect on these parameters in either group. Basal and insulin-stimulated carbohydrate metabolism were assessed using the euglycemic clamp technique in overnight-fasted animals with 3 (H)-6-glucose infusion. As expected, basal hepatic glucose production (HGP) was higher and the metabolic clearance rate of glucose (MCR) was lower in STZ-diabetic rats. High-dose insulin infusion (3 mU · kg −1 · min −1 ) suppressed HGP in nondiabetic and diabetic animals and increased the MCR in nondiabetic animals. However, propionate supplementation did not alter basal or insulin-stimulated HGP or the MCR in either nondiabetic or diabetic animals. It is concluded that oral propionate supplementation had no detectable effect on carbohydrate or lipid metabolism in either nondiabetic or STZ-diabetic rats.

19 citations


Journal ArticleDOI
TL;DR: The level and stereochemistry of the incorporation of deuteriated sodium propionate indicates that it undergoes unexpected modification during incorporation into the cyclopropyl ring.
Abstract: Incorporation of CH313C18O2Na and CD3CH213CO2Na into the indolizidine alkaloid cyclizidine 1, produced by Streptomyces species NCIB 11649, shows that the oxygen attached to C-2 is derived intact from acetate and that the cyclopropyl ring is derived from a single intact propionate unit. However, the level and stereochemistry of the incorporation of deuteriated sodium propionate indicates that it undergoes unexpected modification during incorporation into the cyclopropyl ring.

15 citations


Journal ArticleDOI
TL;DR: It is concluded that the use of propionate in injectibles, drinking water, or feed of newly hatched turkeys is contraindicated.

8 citations


Journal ArticleDOI
TL;DR: In this article, the numbers and locations of deuterium labels were confirmed by broad-band deutereium and proton-decoupled 13C-nuclear magnetic resonance (13C-{1H} {D}NMR) spectroscopy and fast atom bombardment mass (FAB-MS) Spectroscopy.
Abstract: Sodium [3-13C]- and [3-13CD3]propionate were conveniently synthesized from 2,4,4-trimethyl-2-oxazoline. The numbers and locations of deuterium labels were confirmed by broad-band deuterium and proton-decoupled 13C-nuclear magnetic resonance (13C-{1H} {D}NMR) spectroscopy and fast atom bombardment mass (FAB-MS) spectroscopy.

2 citations


Journal ArticleDOI
TL;DR: For example, the authors reported that 5.1% of the users were satisfied with the quality of the service provided by the service provider, and 5.5% of users were dissatisfied with the service.
Abstract: 成メン羊3頭を用い,ルーサンヘイキューブを基礎飼料とし,その総エネルギー量の5.1%に相当するプロピオン酸ナトリウム(Na)あるいは酢酸Naを添加して,ルーメン内環境,窒素出納および15Nトレーサー法による血漿中尿素態窒素とルーメン内アンモニア態窒素の代謝速度を測定した.その結果,プロピオン酸Na添加によって,ルーメンアンモニアの濃度およびイリバーシブルロスの有意な低下と,飼料および尿素以外の内因性窒素に由来するルーメンアンモニア生成およびルーメンアンモニアから血漿中尿素への窒素の移行の減少が認められた.また血漿中尿素濃度は有意に低下し,また尿中へ尿素および総窒素排泄速度が低下して,体内窒素蓄積が増加する傾向にあった.しかし,血漿中尿素態窒素のルーメンアンモニアへの移行速度には変化が認められなかった.以上のことから,飼料へのプロピオン酸Na添加は尿中尿素排泄の抑制によって窒素蓄積を増加させるが,その原因の一つはルーメンでのアンモニア産生に対する抑制効果であり,本実験条件下においてはルーメン内への尿素リサイクル速度には影響しないことが明らかになった.酢酸Na添加の場合にも,窒素代謝の変化はほぼ同様の傾向を示したが,その変化はプロピオン酸Na添加の場合と比較して小さかった.これはルーメン微生物によるアンモニア産生に対する影響が,プロピオン酸と比較して小さかったことが一因であると考えられた.

1 citations


Journal ArticleDOI
TL;DR: Differential thermal analysis and hot-stage polarization microscopy were used to study the phase diagrams of binary systems of sodium, potassium, and cesium propionates as discussed by the authors, and the induction of type-A smectic liquid crystals was observed in the sodium-containing systems.
Abstract: Differential thermal analysis and hot-stage polarization microscopy were used to study the phase diagrams of binary systems of sodium, potassium, and cesium propionates. The induction of type-A smectic liquid crystals was observed in the sodium-containing systems. Liquid crystal formation in systems composed of components, which are individually nonmesomorphic, is attributed to latent mesomorphism of sodium propionate or potassium propionate.