Showing papers on "Sodium propionate published in 2015"

Chemical approach to solvent removal during nanoencapsulation: its application to preparation of PLGA nanoparticles with non-halogenated solvent

Abstract: The objective of this study was to develop a new oil-in-water emulsion-based nanoencapsulation method for the preparation of PLGA nanoparticles using a non-halogenated solvent. PLGA (60–150 mg) was dissolved in 3 ml of methyl propionate, which was vortexed with 4 ml of a 0.5–4 % polyvinyl alcohol solution. This premix was sonicated for 2 min, added into 30 ml of the aqueous polyvinyl alcohol solution, and reacted with 3 ml of 10 N NaOH. Solvent removal was achieved by the alkaline hydrolysis of methyl propionate dissolved in an aqueous phase into water-soluble methanol and sodium propionate. It was a simple but effective technique to quickly harden nanoemulsion droplets into nanoparticles. The appearing PLGA nanoparticles were recovered by ultracentrifugation and/or dialysis, lyophilized with trehalose, and redispersed by water. This nanoencapsulation technique permitted a control of their mean diameters over 151.7 ± 3.8 to 440.2 ± 22.2 nm at mild processing conditions. When the aqueous polyvinyl alcohol concentration was set at ≥1 %, nanoparticles showed uniform distributions with polydispersity indices below 0.1. There were no significant changes in their mean diameters and size distribution patterns before and after lyophilization. When mestranol was encapsulated into nanoparticles, the drug was completely nanoencapsulated: depending on experimental conditions, their encapsulation efficiencies were determined to be 99.4 ± 7.2 to 105.8 ± 6.3 %. This simple, facile nanoencapsulation technique might have versatile applications for the preparation of polymeric nanoparticulate dosage forms. Schematic illustration of an innovative chemical approach to solvent removal during nanoencapsulation. Methyl propionate present in the aqueous continuous phase reacts with sodium hydroxide, thereby producing methanol and sodium propionate. Its alkaline hydrolysis allows the continuous extraction of the solvent out of nanoemulsion droplets, eventually solidifying them into nanoparticles. It is a simple but effective nanoencapsulation technique that has advantages over typical solvent evaporation and/or extraction methods.

Propionate supplementation improves nitrogen use by reducing urea flux in sheep

Abstract: Feeding and postruminal infusion of propionate is known to increase N retention in ruminants. Our aim was to determine the role of rumen propionate on urea N recycling and gluconeogenesis in growing sheep. In Exp. 1, wether sheep ( = 6; 32.5 ± 3.57 kg BW) fitted with a rumen cannula were fed to 1.8 × ME requirement a concentrate-type ration (172 g CP/kg DM and 10.4 MJ ME/kg DM) and continuously infused into the rumen with isoenergetic (10% of dietary ME intake) solutions of either sodium acetate (control) or sodium propionate for 9-d periods in a crossover design. In Exp. 2, a different group of wether sheep ( = 5; 33.6 ± 3.70 kg BW) fitted with a rumen cannula were fed, on an isonitrogenous basis, either a control (151 g CP/kg DM and 8.4 MJ ME/kg DM) or sodium propionate-supplemented (139 g CP/kg DM and 8.9 MJ ME/kg DM) diet at 2-h intervals. [N] urea was continuously infused intravenously for the last 5 d of each period, and total urine was collected by vacuum and feces were collected by a harness bag. Over the last 12 h, [C]glucose was continuously infused intravenously and hourly blood samples were collected during the last 5 h. Propionate treatments increased ( < 0.001) the proportion of rumen propionate in both experiments. In Exp. 1, N retention was not affected by propionate infusion as compared with isoenergetic acetate. There was no effect on urea entry (synthesis) rate (UER) in Exp. 1; however, sodium propionate infusion tended ( < 0.1) to increase urinary urea elimination (UUE). In Exp. 2, feeding propionate increased ( < 0.01) N retention by 0.8 g N/d. In addition, UER was reduced by approximately 2 g urea N/d, leading to a reduction ( < 0.05) in UUE (7.0 vs. 6.2 g urea N/d). Between the 2 experiments, the proportion of UER recycled to the gut was greater with the forage-type diet in Exp. 2 (approximately 60%) compared with the concentrate-type diet in Exp. 1 (approximately 40%), although urea N fluxes across the gut remained unchanged in both experiments. In Exp. 1, glucose entry and gluconeogenesis were greater ( < 0.05) and plasma glucose tended ( < 0.1) to be greater with sodium propionate infusion than with sodium acetate infusion, but there was no difference in Cori cycling. In Exp. 2, glucose entry, gluconeogenesis, Cori cycling, and plasma glucose increased ( < 0.05) with dietary propionate. Our studies indicate that propionate inclusion in feed, but not continuous infusion in to the rumen, improves N utilization in growing sheep. The propionate effect is likely mediated by providing additional precursors for gluconeogenesis.

Composite liquid acidification and mildew resistance agent and preparation method thereof

Abstract: The present invention discloses a composite liquid acidification and mildew resistance agent and a preparation method thereof. The composite liquid acidification and mildew resistance agent includes the following raw materials in parts by mass: 5.0-9.50% of 85% lactic acid, 5.0-9.50% of 85% phosphoric acid, 0.05-0.10% of 50% formic acid, 0.10-0.20% of 95% propionic acid, 3.50-4.50% of 50% dipropylene ammonium, 2.0-3.5% of 50% sodium propionate, 10.0-20.0% glycerin, 10.0-20.0% maltodextrin and 50.0-60.0% of water. The preparation method includes the following steps: evenly mixing six solutions of the 85% lactic acid, the 85% phosphoric acid, the 50% formic acid, the 95% propionic acid, the 50% dipropylene ammonium and the 50% sodium propionate to obtain a mixer; dissolving the maltodextrin in the water completely and then adding the glycerin and carrying out even mixing to obtain another mixer; finally mixing the two mixers and obtaining the composite liquid acidification and mildew resistance agent. The composite liquid acidification and mildew resistance agent prepared by the preparation method in the present invention can overcome the negative effects which are caused by silica carrier on feed intake when using a solid acidifying agent and a solid mildew resistance agent. Therefore, palatability of pig feed can be greatly increased, and the feed intake can be improved.

Safe and non-toxic food preservative

Abstract: The invention discloses a safe and non-toxic food preservative which is prepared from the following raw materials in parts by weight: 6-8 parts of capsicum extract, 11-14 parts of garlic extract, 8-10 parts of epsilon-polylysine, 4-7 parts of sorbic acid, 6-8 parts of dehydroacetic acid, 7-10 parts of nisin, 1.2-2 parts of phenylmalonic acid sodium salt, 5-8 parts of clove oil, 1-3 parts of sodium propionate, 2 -4 parts of starch, 5-8.4 parts of malic acid, 0.5-3 parts of lactic acid and 6-8 parts of starch. The food preservative provided by the invention is good in preservative effect, high in bactericidal capacity, safe and non-toxic, and especially suitable for meat products.

Method for grains preparation to milling

Abstract: FIELD: food industry.SUBSTANCE: method envisages grains washing, one- or two-stage moistening and conditioning; during grains moistening and conditioning at the first and/or the second stage one uses an auxiliary technological agent in an amount of 0.001÷0.05% of the grain dry substances weight; the agent consists of enzyme preparations of hydrolase class (cellulase (KF 3.2.1.4 and KF 3.2.1.91 and/or KF 3.2.1.74) and xylanase (KF 3.2.1.8 and/or KF 3.2.1.55)) and food additives i.e. calcium peroxide (E930) and sodium propionate (E281) and/or calcium propionate (E282) and/or potassium propionate (E283) and/or sodium acetate (E262) and/or calcium acetate (E263), and/or potassium acetate (E261), the temperature of water supplied for hydrothermal treatment being 10÷50°C.EFFECT: prime grade flour yield increase with simultaneous increase of the total flour yield during graded milling and flour biological value increase.2 cl, 2 dwg, 1 tbl

Bean product freshness-retaining preservative

Abstract: The invention relates to a preservative suitable for plant protein, and discloses a bean product freshness-retaining preservative. The bean product freshness-retaining preservative at least comprises the following components in percentage by weight: 20%-25% of sodium propionate, 2 per mill of D-erythorbic acid and 2 per mill of gluconic acid-theta-lactone. The bean product freshness-retaining preservative is reasonable in component, and is synergistically constructed by D-erythorbic acid and sodium propionate, and excellent in stability; not only the preservation effect of the single sodium propionate is improved, but also the preservation effect of the preservative in single component is about the same with that of a composite preservative, thereby reducing the occupied proportion of the preservative and reducing the material cost; and meanwhile, the prepared freshness-retaining preservative is colorless, tasteless and non-toxic, and suitable for food additive, and can be widely applied to the plant protein products such as bean products, canned foods and fruit juice beverage.

Micellization Behaviour of m-E2-m Biodegradable Gemini Surfactants in Presence of Sodium Alkanoates (Sodium Propionate, Sodium Hexanoate, Sodium Decanoate)

Abstract: The present study involves the micellization of novel biodegradable gemini surfactants (1,2-diyl-bis(N,N-dimethyl-N-alkyl-ammoniumacetoxy) dichlorides, m-E2-m; m = 12,14,16 is the number of carbon atoms in the tail and E2 represents the diester-group-containing spacer) in presence of sodium alkanoates (sodium propionate, sodium hexanoate, sodium decanoate). The techniques of tensiometry and spectrofluorimetry were utilized to probe the changes in various physicochemical parameters, viz. critical micellar concentration (CMC), surface excess concentration (Γmax), minimum area per head group (Amin), Gibbs free energy of micellization (ΔG°mic), Gibbs free energy of adsorption (ΔG°ads), aggregation number (Nagg) and local polarity index (I1/I3). Results depict that the alkanoates are effective in bringing significant changes in the physicochemical parameters of the m-E2-m geminis; the order being followed is NaDec > NaHx > NaPr. Both hydrophobic and electrostatic factors were found to be contributive....

Fruit preservation powder and preparation method thereof

Abstract: The invention discloses fruit preservation powder and a preparation method thereof. The preservation powder comprises the following components in percentage by weight: 50-60% of light calcium carbonate, 10-20% of calcium sulfate, 15-25% of talcum powder, 5-7% of sodium propionate and 6-8% of sodium pyrosulfate. The preparation method comprises steps of mixing the light calcium carbonate, the calcium sulfate, the talcum powder, the sodium propionate and the sodium pyrosulfate according to proportions, heating to 70-100 DEG C for 10-15min and stirring to obtain a finished product. The preservation powder disclosed by the invention is excellent in sterilization and preservation functions, the preparation method is scientific and reasonable, simple and easy to implement, and the preservation powder has the advantages of good preservation effect, low cost, etc.

The Influence of Different Carbon Sources for Polyhydroxyalkanoates Storage

Abstract: The influence of different carbon sources such as glucose, sodium acetate, sodium propionate and ethanol for polyhydroxyalkanoates (PHA) storage were studied in details. It was shown that both the cell content and composition of PHA synthesized by microorganisms in activated sludge were different when different carbon sources were used. PHB (polyhydroxybutyrate) was the main PHA if sodium acetate was used as carbon source, while PHV (polydroxyvalerate) become the main PHA when sodium propionate was used. Sodium acetate and sodium propionate as carbon source had higher PHA production, which reached to 40.89% and 40.96% sludge dry weight, respectively . When ethanol used as carbon source, PHA content was 25.69% sludge dry weight. The minimal PHA storage was 20.14% sludge dry weight when glucose was used.

METHOD FOR PRODUCING AN AQUEOUS α-LIPOIC ACID SALT SOLUTION AND USE THEREOF

Abstract: In the present invention, provided are a manufacturing method of a α-lipoic acid salt aqueous solution and uses thereof. In the present invention, provided are a α-lipoic acid salt aqueous solution, which uses alkaline chemicals and sodium benzoate, sodium propionate or mixtures thereof and accordingly increases thermal stability, uses of additive for animal feed thereof and uses thereof as animal feed.

Alfalfa fresh grass storage additive and preparation method thereof

Abstract: The invention discloses an alfalfa fresh grass storage additive and a preparation method thereof. The additive is prepared from sodium benzoate, sodium propionate and water in a weight ratio of (0.38-0.42) to (0.12-0.08) to 1. The preparation method comprises the following steps: weighing the sodium benzoate, the sodium propionate and the water in a proportion firstly; adding the sodium benzoate and the sodium propionate into the water; uniformly stirring to prepare the alfalfa fresh grass storage additive. Alfalfa silage prepared from the alfalfa fresh grass storage additive has the yellow green color and is delicious in taste, and dairy cow like to eat the alfalfa silage; after the alfalfa silage is stored for half a year, the test analysis shows that the content of ammonia nitrogen and butyric acid is very low, and the nutritive value of the stored alfalfa silage is as the same as that of fresh alfalfa; after the alfalfa is stored for one year, the apparent identification shows that the content of the alfalfa is still in a normal level; alfalfa silage dairy cow feeding tests show that after the dairy cow are fed with the alfalfa silage, the milk production and the feed conversion ratio can be increased; in the test period of the whole three months, tested cow have no bad symptoms and are good in health condition.

Method for preparing powder metallurgy lubricants

Abstract: The invention provides a method for preparing powder metallurgy lubricants. The method includes stirring and mixing microcrystalline wax, nanometer silicon dioxide and oleic acid with one another to obtain first mixtures, heating the first mixtures, adding alkyl diphenylamine, chlorinated polyethylene and mullite into the first mixtures, mixing the alkyl diphenylamine, the chlorinated polyethylene, the mullite and the first mixtures with one another to obtain second mixtures, heating the second mixtures, stirring the second mixtures under a heat-insulation condition, and cooling the second mixtures until the temperatures of the second mixtures reach the room temperature to obtain mixtures A; heating sodium stearyl lactate, acrylamide, ammonium persulfate, methacrylic acid-dimethylamino ethyl ester, octadecyl dimethyl tertiary amine sodium propionate and sodium hexametaphosphate, stirring the sodium stearyl lactate, the acrylamide, the ammonium persulfate, the methacrylic acid-dimethylamino ethyl ester, the octadecyl dimethyl tertiary amine sodium propionate and the sodium hexametaphosphate under vacuum heat-insulation conditions, and cooling the sodium stearyl lactate, the acrylamide, the ammonium persulfate, the methacrylic acid-dimethylamino ethyl ester, the octadecyl dimethyl tertiary amine sodium propionate and the sodium hexametaphosphate until the temperatures of the sodium stearyl lactate, the acrylamide, the ammonium persulfate, the methacrylic acid-dimethylamino ethyl ester, the octadecyl dimethyl tertiary amine sodium propionate and the sodium hexametaphosphate reach the room temperature to obtain mixtures B; mixing the mixtures A and the mixtures B with one another and carrying out ball-milling on the mixtures A and the mixtures B to obtain the powder metallurgy lubricants. The method has the advantages that the flow rates of the powder metallurgy lubricants can reach 3.4g/s at least, the apparent density of the powder metallurgy lubricants can reach 3.54g/cm approximately, the compact density of the powder metallurgy lubricants can reach 2.32g/cm approximately, mechanical properties of iron-based powder metallurgy materials can be improved, and the comprehensive performance of the powder metallurgy lubricants can be greatly enhanced as compared with micro-powder wax.

Rust remover for surface of powder metallurgy material and preparation method of rust remover

Abstract: The invention discloses a rust remover for the surface of powder metallurgy material and a preparation method of the rust remover. The rust remover comprises sodium hexametaphosphate, potassium sulfate, octadecyl dimethyl tertiary amine sodium propionate, emulsified silicone oil, magnesium stearate, sodium nitrate, ethyl acetate, silicon dioxide, maleic anhydride, acetic anhydride, ethylenediamine tetraacetic acid, hydroxymethanesulfinic acid sodium salt dihydrate and water. The preparation method of the rust remover comprises the following steps: adding magnesium stearate, ethyl acetate, maleic anhydride, acetic anhydride and ethylenediamine tetraacetic acid into a container, stirring and mixing uniformly to obtain a mixture I; then adding sodium hexametaphosphate, potassium sulfate, octadecyl dimethyl tertiary amine sodium propionate, emulsified silicone oil, sodium nitrate, silicon dioxide and hydroxymethanesulfinic acid sodium salt dehydrate to water and mixing uniformly to obtain a mixture II; and finally homogenizing the mixture I and the mixture II in a high-pressure homogenizer to obtain the rust remover. The rust remover for the surface of powder metallurgy material, provided by the invention, is capable of rapidly removing rust from the surface of powder metallurgy material and providing an excellent rust removal and protective function at the same time.

Preparation method of S-2-(4-methoxyphenoxy) sodium propionate

Abstract: The invention discloses a preparation method of S-2-(4-methoxyphenoxy) sodium propionate serving as a high optically-active sweet inhibitor. The preparation method comprises the steps of reacting D-substituted lactate with substituted benzene sulfonyl chloride to generate a corresponding R-substituted sulfonyl lactate; then reacting the obtained R-substituted sulfonyl lactate with p-methoxy phenate in a solvent to generate S-2-(4-methoxyphenoxy) propionate; and hydrolyzing and acidifying the obtained ester, and then reacting with an alkali containing sodium ions, thus obtaining the S-2-(4-methoxyphenoxy) sodium propionate. The preparation method of the S-2-(4-methoxyphenoxy) sodium propionate is developed for the first time. The obtained S-2-(4-methoxyphenoxy) sodium propionate has high optical purity; and when being measured by a sense method, the S-2-(4-methoxyphenoxy) sodium propionate has a better sweet inhibiting effect on sucrose compared with raceme, and can reduce the metabolic burden of R-type non-active ingredients of the raceme in human bodies and eliminate potential harm to the human bodies.

Effects of Storage Type and Inclusion of Sodium Propionate on Microbial Profile of Feed Ingredients Commonly Used in Pig Diets

Abstract: An experiment was conducted to investigate the effects of storage type and inclusion of antifungal agent (sodium propionate) on microbial profile of feed ingredients commonly used in pig diets. Total of six feed ingredients (corn, wheat, soybean meal (SBM), corn DDGS, fish meal and poultry by-products) were stored in granary or feed bin with or without antifungal agent (0.30% sodium propionate) for 8 weeks period and microbial profile were investigated at the beginning of the experiment (week 0) and at 2, 4, 6 and 8 weeks of storage. At the beginning of the experiment, microbial profile of all feed ingredients were not different (p>0.05) among ingredients stored in granary or feed bin with or without sodium propionate. Irrespective of storage type and addition of sodium propionate, salmonella was not detected in any of all feed ingredient during 8 weeks of storage period. Inclusion of sodium propionate reduced (p 0.05) on populations of staphylococci, clostridia, coliforms, total bacterial count, yeast and mold counts during any storage period. The results obtained in the present study indicated that microbial profile of feed ingredients was not affected by storage type (granary vs. feed bin), but the inclusion of sodium propionate improved the microbial profile of all feed ingredients commonly used in pig diets.

Yeast-enriched identification medium for inhibiting mycetes and preparation method of yeast-enriched identification medium

Abstract: The invention provides a yeast-enriched identification medium for inhibiting mycetes and a preparation method of the yeast-enriched identification medium. The identification medium comprises the following ingredients by weight percent: 1+/-0.2% of yeast powder, 2+/-0.2% of peptone, 2+/-0.2% of glucose, 2+/-0.2% of agar, 4 +/-0.2% of a stock solution A, 0.1 +/-0.2% of a stock solution B, 2.2 +/-0.2% of sodium propionate and the balance of water, and the natural pH is 6.5 +/-0.2. The preparation method comprises the following steps: step A: preparing a basal medium, the stock solution A and the stock solution B according to the formula; step B: adding yeast powder, peptone, glucose, agar and water respectively according to the formula, uniformly mixing, adding the stock solution A and the stock solution B, then adding sodium propionate, so as to enable the natural pH of the medium to reach to 6.5 +/-0.2, sterilizing for 20 minutes at 121+/-0.2 DEG C, and after sterilization adding chloramphenicol and a stock solution C. By adopting the scheme, the mycete bacteria contamination in nature can be effectively inhibited, and the effects of yeast-enriched cultivation and preliminary identification are achieved.

Preparation method of S-2-(4-methoxyphenoxy) sodium propionate

Abstract: The invention discloses a preparation method of S-2-(4-methoxyphenoxy) sodium propionate serving as a high optically-active sweet inhibitor. The preparation method comprises the steps of reacting D-substituted lactate with substituted benzene sulfonyl chloride to generate a corresponding R-substituted sulfonyl lactate; then reacting the obtained R-substituted sulfonyl lactate with p-methoxy phenate in a solvent to generate S-2-(4-methoxyphenoxy) propionate; and hydrolyzing and acidifying the obtained ester, and then reacting with an alkali containing sodium ions, thus obtaining the S-2-(4-methoxyphenoxy) sodium propionate. The preparation method of the S-2-(4-methoxyphenoxy) sodium propionate is developed for the first time. The obtained S-2-(4-methoxyphenoxy) sodium propionate has high optical purity; and when being measured by a sense method, the S-2-(4-methoxyphenoxy) sodium propionate has a better sweet inhibiting effect on sucrose compared with raceme, and can reduce the metabolic burden of R-type non-active ingredients of the raceme in human bodies and eliminate potential harm to the human bodies.