Topic
Solid lipid nanoparticle
About: Solid lipid nanoparticle is a research topic. Over the lifetime, 3175 publications have been published within this topic receiving 127912 citations. The topic is also known as: LNP & SLN.
Papers published on a yearly basis
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TL;DR: Delivering RSV by SLN contributes to effectiveness of RSV on decreasing cell proliferation, with potential benefits for prevention of skin cancer.
241 citations
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TL;DR: In this article, particle internalization by granulocytes was followed using luminol enhanced chemiluminescence (CL) to assess their toxicological acceptance as intravenous formulation for magnetic resonance imaging and as potential carrier for drug targeting.
241 citations
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TL;DR: Results of stability evaluation showed a relatively long-term stability after storage at 4 degrees C for 6 months and SLNs with small particle size, excellent physical stability, high entrapment efficiency, good loading capacity for protein drug can be produced by this novel reverse micelle-double emulsion method.
240 citations
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TL;DR: Techniques to characterize drug loading to carrier systems and skin penetration profiles by using the lipophilic dye nile red as a model agent are described and drug targeting appears to be more strictly related to the mode of interaction of drug and particle than penetration enhancement.
239 citations
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TL;DR: Solid Lipid Nanoparticles (SLN) as discussed by the authors can be used as a drug reservoir providing controlled drug release by melting the lipid matrix material and dissolving the drug in the melted lipid.
237 citations