Topic
Solid lipid nanoparticle
About: Solid lipid nanoparticle is a research topic. Over the lifetime, 3175 publications have been published within this topic receiving 127912 citations. The topic is also known as: LNP & SLN.
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TL;DR: DO-FUdR-SLN can improve the ability of the drug to penetrate through the blood-brain barrier and is a promising drug targeting system for the treatment of central nervous system disorders.
168 citations
TL;DR: The NLC is described with respect to structures, methods of preparation, characterization, stability and its advantages over first generation lipid nanoparticles.
167 citations
TL;DR: The development and characterize of a solid lipid nanoparticle (SLN) system containing an anionic polymer for the delivery of cationic antineoplastic agents and chemosensitizers laid the foundation for a "one-bullet" dosage form that may provide convenient and effective delivery of multiple drug treatment of tumors.
167 citations
TL;DR: It could be shown that the occlusion factor depends strongly on the degree of crystallinity of the lipid matrix, i.e. this effect is proportional and the desired degree of occlusivity can be achieved by choosing suitable lipids for the matrices of topical SLN formulations.
167 citations
TL;DR: This review evaluates recent advances in the development of phytochemical oral delivery systems, including microemulsions, nanoemulsion, emulsion, solid lipid nanoparticles, liposomes, and biopolymer microgels.
167 citations