Solid lipid nanoparticle

TL;DR: The unique advantages and disadvantages of polymeric nanoparticles, liposomes, solid lipid nanoparticles and lipid-coated nanoparticles for targeted drug delivery will be investigated in detail.

TL;DR: It can be concluded from this study that NLCs provide a good skin targeting effect and may be a promising carrier for topical delivery of FLZ offering the sustained release and maintain the localized effect, resulting in an effective treatment of a life-threatening cutaneous fungal infection.

TL;DR: The in vitro experiments demonstrated that gamma sterilisation is a suitable process for the final sterilisation because no loss in activity was observed after the sterilisation process and the proliferation assays revealed that the bioactivity of the nanoformulations was even higher than that of free rhEGF.

TL;DR: The impact of carrier oil composition and physical state on the physical and chemical stability of lipid nanoparticles containing encapsulated β-carotene was investigated in this article, where the authors found that the particle particle particle d C was ≈ 20 for SLN and ≈ 12 for LLN and attributed the ability of the fat crystals within the lipid particle to promote partial coalescence and expulsion of carotenoids to the particle exterior.

TL;DR: The polymorphic transitions of the triglycerides were slower in the presence of egg and saturated lecithin leading to a higher stability of the metastable alpha-form and the possibility to prepare triglyceride nanoparticles stable in specific modifications offers new opportunities to study effects of polymorphic form on colloidal stability, drug loading and release properties of such dispersions.