Topic
Somatosensory system
About: Somatosensory system is a research topic. Over the lifetime, 6371 publications have been published within this topic receiving 316900 citations.
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TL;DR: Findings provide novel evidence for successive neuron loss within the thalamus and cortex in Ppt1-/- mice, revealing theThalamus as an important early focus of INCL pathogenesis.
167 citations
TL;DR: FMRI data provides evidence that both SI and SII encode spatial information of nociceptive stimuli without additional information from the tactile system and highlights the concept of a redundant representation of basic discriminative stimulus features in human somatosensory cortices, which seems adequate in view of the evolutionary importance of pain perception.
166 citations
TL;DR: The present data suggest several compensatory changes in both auditory and somatosensory modalities after the onset of early visual deprivation, which appears to indicate enhanced automatic processing of auditory stimulus changes in the blind.
Abstract: Previous event-related potential (ERP) studies have suggested a possible participation of the visual cortex of the blind in auditory processing. In the present study, somatosensory and auditory ERPs of blind and sighted subjects were recorded when subjects were instructed to attend to stimuli of one modality and to ignore those of the other. Both modalities were stimulated with frequent (“standard”) and infrequent (“deviant”) stimuli, which differed from one another in their spatial locus of origin. In the sighted, deviant stimuli of the attended modality elicited N2 type of deflections (auditory N2b and somatosensory N250) over the lateral scalp areas. In contrast, in the blind, these ERP components were centroposteriorly distributed, suggesting an involvement of posterior brain areas in auditory and somatosensory stimulus discrimination. In addition, the mismatch negativity, elicited by deviant auditory stimuli even when the somatosensory stimuli were attended, was larger in the blind than in the sighted. This appears to indicate enhanced automatic processing of auditory stimulus changes in the blind. Thus, the present data suggest several compensatory changes in both auditory and somatosensory modalities after the onset of early visual deprivation.
166 citations
TL;DR: The SMA may provide an efferent signal which is used by other brain areas to modulate somatosensory activity during self-generated movement, and is suggested to reduce and almost abolished the sensory suppression effect in voluntary action trials.
165 citations
TL;DR: It is shown that CC-projecting cells encompass a broad spectrum of selectivity to stimulus orientation and are predominantly innervated by deep layer V1 neurons, and CT- Projecting cells are ultrasparse firing, exquisitely tuned to orientation and direction information, and receive long-range input from higher cortical areas.
165 citations