Topic
Sperm motility
About: Sperm motility is a research topic. Over the lifetime, 13874 publications have been published within this topic receiving 416587 citations. The topic is also known as: sperm movement & GO:0097722.
Papers published on a yearly basis
Papers
More filters
TL;DR: The results suggest that atrazine impairs reproductive function and elicits a depletion of the antioxidant defense system in the testis and epididymis, indicating the induction of oxidative stress.
Abstract: To study the effects of atrazine on reproductive functions and testicular and epididymal antioxidant defense, rats were exposed to 0, 120, or 200 mg/kg body weight atrazine orally for 7 and 16 days. Animals exposed to the high-dose atrazine had their body weights, feed intake, and reproductive organs weights significantly reduced, whereas testicular weights remain unaffected independent of the dose used. In comparison to control, glutathione (GSH) and glutathione-S-transferase (GST) activities were elevated in the high-dose group, whereas the activity of superoxide dismutase (SOD), catalase (CAT); ascorbate (AA), and malondialdehyde (MDA) levels and hydrogen peroxide production were unchanged in the testis during the 7-day-exposure protocol. When atrazine treatment was increased to 16 days, GSH levels remained unchanged, but lipid peroxidation levels were significantly increased in both the testes and epididymides. This corresponded to the significant diminution in the activities of GST and SOD. CAT activities were unaffected in the testes and then dropped in the epididymides. γ-Glutamyl transferase (γ-GT) activities increased during both studies, whereas AA levels remained unaffected (p < 0.05). Atrazine exposure has a dose-dependent adverse effect on the testicular and epididymal sperm numbers, motility, viability, morphology, and daily sperm production. Although the testes of the atrazine-treated animals appear normal, few tubules had mild degeneration with the presence of defoliated cells. Likewise, no perceptible morphological changes were observed in the epididymis. The results suggest that atrazine impairs reproductive function and elicits a depletion of the antioxidant defense system in the testis and epididymis, indicating the induction of oxidative stress.
135 citations
TL;DR: This work shows that Calr3−/− males produced apparently normal sperm but were infertile because of defective sperm migration from the uterus into the oviduct and defective binding to the zona pellucida, and establishes the client specificity of CALR3.
135 citations
TL;DR: This review briefly summarizes the key components involved in pHi regulation, their characteristics and participation in fundamental sperm functions such as motility, maturation and the acrosome reaction.
135 citations
TL;DR: A set of criteria have been identified that accurately predict the fertilizing potential of human sperm suspensions in vitro and that place particular emphasis on sperm morphology and the degree of leukocyte contamination.
135 citations
TL;DR: Results indicate that progestins can also exert rapid actions in the preoptic anterior hypothalamus (POAH) in this species to down-regulate gonadotropin-releasing hormone (GnRH) secretion and act on Atlantic croaker spermatozoa via an mPR to rapidly increase sperm motility.
134 citations