Showing papers on "Sterculia foetida published in 2008"

Evaluation of Sterculia foetida Gum as Controlled Release Excipient

Abstract: The purpose of the research was to evaluate Sterculia foetida gum as a hydrophilic matrix polymer for controlled release preparation For evaluation as a matrix polymer; characterization of Sterculia foetida gum was done Viscosity, pH, scanning electronmicrographs were determined Different formulation aspects considered were: gum concentration (10–40%), particle size (75–420 μm) and type of fillers and those for dissolution studies; pH, and stirring speed were considered Tablets prepared with Sterculia foetida gum were compared with tablets prepared with Hydroxymethylcellulose K15M The release rate profiles were evaluated through different kinetic equations: zero-order, first-order, Higuchi, Hixon-Crowell and Korsemeyer and Peppas models The scanning electronmicrographs showed that the gum particles were somewhat triangular The viscosity of 1% solution was found to be 950 centipoise and pH was in range of 4–5 Suitable matrix release profile could be obtained at 40% gum concentration Higher sustained release profiles were obtained for Sterculia foetida gum particles in size range of 76–125 μm Notable influences were obtained for type of fillers Significant differences were also observed with rotational speed and dissolution media pH The in vitro release profiles indicated that tablets prepared from Sterculia foetida gum had higher retarding capacity than tablets prepared with Hydroxymethylcellulose K15M prepared tablets The differential scanning calorimetry results indicated that there are no interactions of Sterculia foetida gum with diltiazem hydrochloride It was observed that release of the drug followed through surface erosion and anomalous diffusion Thus, it could be concluded that Sterculia foetida gum could be used a controlled release matrix polymer

Physico-Chemical and Viscosity Studies in Some Seed Oils from Wild and Cultivated Plants

Abstract: Physico-chemical properties ofMadhuca longifolia L, Sterculia foetida L and Hibiscus cannabinus L seed oils were investigated. M. longifolia has significantly high oil content. These determined parameters have been compared with the literature and discussed. The temperature dependence of density and absolute viscosity in these oils has been determined over the temperature range from 303 K to 343 K. The values of density and absolute viscosity in these oils are comparable with that reported for other similar kind of oils. Both density and viscosity decreased monotonically with increase in temperature. Empirical relations which describe the temperature dependence of absolute viscosity were fit to the experimental data and the correlation constants for the best fits are presented and discussed.