Topic
Sterol
About: Sterol is a research topic. Over the lifetime, 8117 publications have been published within this topic receiving 309926 citations. The topic is also known as: sterols & sterol lipids.
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TL;DR: Lanosterol and 4,4-dimethylcholesta-8,24-dien-3 beta-ol were detected in all species studied, and squalene was identified in a stock of L. tropica.
112 citations
TL;DR: The objective of the present study was to ascertain whether the requirement for a cholesterol-type sterol by Dermestes is absolute, and whether cholesterol, according to this hypothesis, can perform both of these functions.
112 citations
TL;DR: Structural and catalytic properties of a potential M. tuberculosis drug target enzyme are revealed, and the likely mode by which the host-derived substrate is bound and hydroxylated is revealed.
111 citations
TL;DR: Dehydration caused a general decrease in the unsaturation level of individual phospholipids and total lipids as well, and upon rehydration the lipid composition of leaf plasma membranes restored very quickly approaching the levels of well-hydrated leaves.
Abstract: Plants of Ramonda serbica were dehydrated to 3.6% relative water content (RWC) by withholding water for 3 weeks, afterwards the plants were rehydrated for 1 week to 93.8% RWC. Plasma membranes were isolated from leaves using a two-phase aqueous polymer partition system. Compared with well-hydrated (control) leaves, dehydrated leaves suffered a reduction of about 75% in their plasma membrane lipid content, which returned to the control level following rewatering. Also the lipid to protein ratio decreased after dehydration, almost regaining the initial value after rehydration. Lipids extracted from the plasma membrane of fully-hydrated leaves were characterized by a high level of free sterols and a much lower level of phospholipids. Smaller amounts of cerebrosides, acylated steryl glycosides and steryl glycosides were also detected. The main phospholipids of control leaves were phosphatidylcholine and phosphatidylethanolamine, whereas sitosterol was the free sterol present in the highest amount. Following dehydration, leaf plasma membrane lipids showed a constant level of free sterols and a reduction in phospholipids compared with the well-hydrated leaves. Both phosphatidylcholine and phosphatidylethanolamine decreased following dehydration, their molar ratio remaining unchanged. Among free sterols, the remarkably high cholesterol level present in the control leaves (about 14 mol%) increased 2-fold as a result of dehydration. Dehydration caused a general decrease in the unsaturation level of individual phospholipids and total lipids as well. Upon rehydration the lipid composition of leaf plasma membranes restored very quickly approaching the levels of well-hydrated leaves.
111 citations
TL;DR: In this article, it was shown that the storage properties of these protein products would be adversely affected by the polyunsaturated fatty acids in these bound fractions, whereas neutral lipids were also a major component in the bound lipid of protein concentrates.
Abstract: Phosphatidylcholine, -inositol and -ethanolamine represented 48, 18 and 8%, respectively, of the total phospholipids in medium and low erucic acid rapeseed. Oleic acid was the principal fatty acid in phosphatidylcholine and -ethanolamine but all components contained high levels of linoleic and saturated acids. There were eight components in the glycolipid fraction of which digalactosyl diglyceride, monogalactosyl diglyceride, sterol glycoside, esterified sterol glucoside and cerebrosides were identified. Defatted flours contained 2.0–3.5% of bound lipid which was composed primarily of phospholipids and glycolipids whereas neutral lipids were also a major component in the bound lipids of protein concentrates. The storage properties of these protein products would be adversely affected by the polyunsaturated fatty acids in these bound fractions.
111 citations