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Stressor

About: Stressor is a research topic. Over the lifetime, 5192 publications have been published within this topic receiving 225733 citations. The topic is also known as: Stresser.


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Journal ArticleDOI
TL;DR: Early life stress has long-term effects on the hypothalamic-pituitary-adrenal axis response to stressors, and has been reported to lead to neuroinflammation, altered levels of neurotrophic factors, modifications in neurogenesis and synaptic plasticity, with changes in neurotransmitter systems and network functioning as discussed by the authors .

2 citations

Journal ArticleDOI
TL;DR: In this paper , the authors assessed whether social support affects the likelihood of depression development differently across the spectrum of genomic risk in two samples that experienced substantial life stress: 1,011 first-year training physicians (interns) in the Intern Health Study (IHS) and 435 recently widowed Health and Retirement Study (HRS) participants.
Abstract: OBJECTIVE Despite substantial progress in identifying genomic variation associated with major depression, the mechanisms by which genomic and environmental factors jointly influence depression risk remain unclear. Genomically conferred sensitivity to the social environment may be one mechanism linking genomic variation and depressive symptoms. The authors assessed whether social support affects the likelihood of depression development differently across the spectrum of genomic risk in two samples that experienced substantial life stress: 1,011 first-year training physicians (interns) in the Intern Health Study (IHS) and 435 recently widowed Health and Retirement Study (HRS) participants. METHODS Participants' depressive symptoms and social support were assessed with questionnaires that were administered before and after the life stressor. Polygenic risk scores (PRSs) for major depressive disorder were calculated for both samples. RESULTS Depressive symptom scores increased by 126% after the start of internship in the IHS sample and by 34% after widowing in the HRS sample. There was an interaction between depression PRS and change in social support in the prediction of depressive symptoms in both the IHS sample (incidence rate ratio [IRR]=0.96, 95% CI=0.93, 0.98) and the HRS sample (IRR=0.78, 95% CI=0.66, 0.92), with higher depression PRS associated with greater sensitivity to changes in social support. Johnson-Neyman intervals indicated a crossover effect, with losses and gains in social support moderating the effect of PRS on depressive symptoms. (Johnson-Neyman interval in the IHS sample, -0.02, 0.71; in the HRS sample, -0.49, 1.92). CONCLUSIONS The study findings suggest that individuals with high genomic risk for developing increased depressive symptoms under adverse social conditions also benefit more from nurturing social environments.

2 citations

Journal ArticleDOI
TL;DR: In this paper , the buffering effect of supportive relationships by testing whether participation in a relationship enhancement program (ProSAAF) that improves couple functioning subsequently buffers the effect of cumulative financial strain on biological aging (weathering).
Abstract: Black adults in the rural South experience elevated financial strain and other contextual stressors, increasing their risk for poor health. Supportive relationships, particularly positive romantic relationships, have been shown to offset these risks. The present study aims to provide experimental evidence of the buffering effect of supportive relationships by testing whether participation in a relationship enhancement program (ProSAAF) that improves couple functioning (Barton, Beach, Wells, et al., 2018) subsequently buffers the effect of cumulative financial strain on biological aging (weathering). Postintervention financial strain was assessed four times. Deoxyribonucleic acid (DNA) was extracted from peripheral whole blood collected 6 years after baseline (n = 348 individuals), and patterns of methylation were used to index accelerated pace of aging. Couple functioning was treated as a latent construct comprising four self-report indicators: effective communication, relationship confidence, relationship satisfaction, and perceived partner support. Results indicated that cumulative financial strain was associated with accelerated pace of aging with a medium to large effect size. This effect was moderated by change in couple functioning such that individuals with greater improvement in couple functioning showed less epigenetic aging in response to cumulative financial strain. Additionally, there was a significant indirect buffering effect of ProSAAF on the association between cumulative financial strain and accelerated pace of aging. This is the first study to demonstrate that a couple-focused preventive intervention can reduce the impact of financial strain on rate of aging by enhancing couple functioning. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

2 citations

Dissertation
18 Sep 2015
TL;DR: Burnout syndrome or combustion marks disagreement between work place demands and personal possibilities, desires and expectations for these demands to meet as mentioned in this paper, which can have adverse effect on interpersonalization and family relations and can lead to general negative attitude toward life.
Abstract: Nurses are working on improving of health care, disease prevention, healing and rehabilitation. They are helping patients in their problems with reduction and supporting them because of diseases, prescribed searches, ways of healing, hospital treatment and family separation. Stress is an answer of organism when meets with events, situations, people or objects that perceived as stress what is consequently inducing answer on stress what is primary for survival. Work stress is type of stress whose source is work environment, and it's defined as general arousal of organism because of uncertain outcome. Burnout syndrome or combustion marks disagreement between work place demands and personal possibilities, desires and expectations for these demands to meet. Health profession have high resposibility for human life, health and she is exposed to specific stressors like chemical, biological and physical harmfulness also as shift work and it's classified as highly stressful profession. Burnout syndrom depends on the person, work organization, work conditions and relationships with colleagues. Immature, overly responsible and ambitious, neurotical and unbalanced, persons that have too high expectations and that are devoting too much time to the job are the persons that are more likely to be affected with burnout syndrome. Problem solutions are often far and uncertain, what is on assistants working as disheartening. Burnout syndrome can make problems in every aspect of individual human life. Burnout can have adverse effect on interpersonalization and family relations and can lead to general negative attitude toward life. No matter what of above sources are mostly contributing to burnout, assistant is emotionaly and physically exhausted.

2 citations

Journal ArticleDOI
TL;DR: Considerably high prevalence of stress was self-reported by new medical undergraduate entrants and academic related factors were greater sources of stress when compared to non-academic factors in these participants.
Abstract: Objectives: The past decade has seen a globally increasing trend in the prevalence of stress among medical students The objectives of our study were to assess stress prevalence, sources of stress and their severity and to assess the determinants of stressed cases in new undergraduate medical entrants Methods: Two hundred and fourteen students (M=130, F=84), who had just completed their first week in the institute, participated voluntarily in a cross-sectional, self-administered questionnaire based study After collecting demographic data, the prevalence of stress was assessed using the 12 item General Health Questionnaire (GHQ-12) and sources of stress and their severity by the 40 item Medical Students Stressor Questionnaire (MSSQ) Results: Demographic characteristics of male and female participants were comparable Prevalence of stress was 421% (M=27% F=17%) of which almost 8% had severe stress The severity of academically related stressors was found to be the highest among medical students, with approximately one-third (341%) of the participants perceiving them to be causing high or severe stress Self rated severity of all other stressor domains was either mild or moderate in more than 85% of the participants There was a significant correlation of GHQ with total MSSQ scores (r=048, p Conclusion: Considerably high prevalence of stress was self-reported by new medical undergraduate entrants Academic related factors were greater sources of stress when compared to non-academic factors in these participants

2 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
20242
20232,066
20224,557
2021456
2020302
2019281