Showing papers on "Strychnos nux-vomica published in 2014"
TL;DR: Stryvomicine A (1), deoxy-isostrychnine-chloromethochloride (2), β-colubrine-chlorine (3) and α-coluba-chloride (4) were isolated from the seeds of Strychnos nux-vomica as mentioned in this paper.
7 citations
01 Jan 2014
TL;DR: The treatments caused pupal mortality and abnormal development in the adult moths, but the treatments did not show any larval mortality against H. armigera.
Abstract: Hexane, chloroform, ethyl acetate and methanol extracts of Strychnos nux-vomica Linn. (Family: Loganiaceae) and Semecarpus anacardium Linn. (Family: Anacardiaceae) were incorporated in semi-synthetic diet at 0.5, 1.0, 1.5 and 2% concentrations. Screened for antifeedant, larvicidal, pupicidal and adult malformation activities against Helicoverpa armigera (Lepidoptera: Noctuidae). The chloroform extract of S. anacardium seeds presented the highest antifeedant activity (74.27%) at 2% concentration. Hexane extract of S. nux-vomica seeds recorded 70.57% antifeedant activity. These two seed extracts did not show any larval mortality against H. armigera. But the treatments caused pupal mortality and abnormal development in the adult moths. Methanol extract of S. anacardium seeds recorded 28.57% pupicidal activity at 2% concentration and hexane extract of S. nux-vomica produced 31.43% of deformed adults. © 2014 Universal Research Publications. All rights reserved
4 citations
TL;DR: In this paper, the antibacterial activity of Strychnos nux vomica leaves showed inhibitory effects on selective bacteria which could be used to control these microbes, but Salmonella typhimurium survived the inhibition.
Abstract: Strychnos nux vomica is a non edible tree with a strong content of two poisonous alkaloids, strychnine and brucine. Qualitative phytochemical analysis and antimicrobial activity of the aqueous methanolic extract of its leaves were studied. Alkaloids, triterpenes, oils & fats, phenol, tannins and flavonoids were present. Escherichia coli Enterobacter, Staphylococcus aureus, and Pseudomonas showed susceptibility but Salmonella typhimurium survived the inhibition. Minimal inhibitory concentration of the extract for E. coliafter an overnight incubation was found to be 0.25 mg. In the present study the antibacterial activity of Strychnos nux vomica leaves showed inhibitory effects on selective bacteria which could be used to control these microbes.
2 citations
Journal Article•
TL;DR: In this article, the authors analyzed Strychnous nux vomica L(SNV) and Ophiorrhiza rugosa wall(OR) for their phytochemical constituents and minerals.
Abstract: Medicinal plants are the nature gifts to human to lead disease free healthy life. The examination of plants for bioactive secondary metabolites is an area which most scientist have recently focused. Strychnous nux vomica L(SNV) and Ophiorrhiza rugosa Wall(OR) are endangered plants of the family Loganiaceae and Rubiaceae respectively .In the present study they were analyzed for their phytochemical constituents and minerals. The study revealed the presence of alkaloids, phenols, flavonoids by qualitative analysis. The total phenolic content was 0.143mg and 0.3297mg/mg respectively in the methanol extract of S.nux vomica and chloroform extract of O.rugosa. Mineral analysis showed the presence of Fe, Na, Mg, Mn, Zn and Cu in both the plants and Cd and Pb are absent in both the plants.
2 citations
TL;DR: In this paper, the effect of particle size on the quality uniformity and in vitro release performance of Strychnos nux-vomica powder with different particle sizes was explored.
Abstract: To explore the effect of particle size on the quality uniformity and in vitro release performance of Strychnos nux-vomica powder, seven samples of Strychnos nux-vomica powder with different particle sizes were prepared. Microstructures and particle sizes were analyzed, and high performance liquid chromatography (HPLC) was used to test the contents and in vitro release performances of brucine and strychnine in the samples. Results showed that the contents and the in vitro release rates of brucine (or strychnine) in different samples were different since there are different proportions of endosperms to epidermal cells in Strychnos nux-vomica powder with different particle sizes. Brucine and strychnine in each sample were promptly released in the first ten minutes and their cumulative release rates were higher than 70% after ten minutes. Eighty minutes later, the cumulative release rate tended to be a constant. Considering the quality uniformity and safety of Strychnos nux-vomica powder used as traditional Chinese medicine, it would be better to control the particle size of Strychnos nux-vomica powder between 100 and 140 mesh in which the maximum cumulative release rate in vitro of brucine and strychnine can be relatively low within this range.
1 citations
01 Jan 2014
TL;DR: In this paper, the authors analyzed Strychnous nux vomica L(SNV) and Ophiorrhiza rugosa wall(OR) for their phytochemical constituents and minerals.
Abstract: Medicinal plants are the nature gifts to human to lead disease free healthy life. The examination of plants for bioactive secondary metabolites is an area which most scientist have recently focused. Strychnous nux vomica L(SNV) and Ophiorrhiza rugosa Wall(OR) are endangered plants of the family Loganiaceae and Rubiaceae respectively .In the present study they were analyzed for their phytochemical constituents and minerals. The study revealed the presence of alkaloids, phenols, flavonoids by qualitative analysis. The total phenolic content was 0.143mg and 0.3297mg/mg respectively in the methanol extract of S.nux vomica and chloroform extract of O.rugosa. Mineral analysis showed the presence of Fe, Na, Mg, Mn, Zn and Cu in both the plants and Cd and Pb are absent in both the plants.