Topic
Surface modification
About: Surface modification is a research topic. Over the lifetime, 35544 publications have been published within this topic receiving 859567 citations.
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TL;DR: An overview of the use of plasma surface modification of biomedical polymers and the influence on cell-material interactions is given and how blood compatibility can be improved by preventing protein adhesion is discussed.
Abstract: Polymers are commonly used in industry because of their excellent bulk properties, such as strength and good resistance to chemicals. Their surface properties are for most application inadequate due to their low surface energy. A surface modification is often needed, and plasma surface modification is used with success the past decades. In the past few years, also plasma surface modification for biomedical polymers has been investigated. For biomedical polymers, the surface properties need to be altered to promote a good cell adhesion, growth and proliferation and to make them suitable for implants and tissue engineering scaffolds. This review gives an overview of the use of plasma surface modification of biomedical polymers and the influence on cell-material interactions. First, an introduction on cell-material interaction and on antibacterial and antifouling surfaces will be given. Also, different plasma modifying techniques used for polymer surface modification will be discussed. Then, an overview of literature on plasma surface modification of biopolymers and the resulting influence on cell-material interaction will be given. After an overview of plasma treatment for improved cell-material interaction, plasma polymerization and plasma grafting techniques will be discussed. Some more specialized applications will be also presented: the treatment of 3D scaffolds for tissue engineering and the spatial control of cell adhesion. Antibacterial and antifouling properties, obtained by plasma techniques, will be discussed. An overview of research dealing with antibacterial surfaces created by plasma techniques will be given, antifouling surfaces will be discussed, and how blood compatibility can be improved by preventing protein adhesion.
192 citations
TL;DR: A plasma treatment that renders asymmetric polysulfone membranes permanently hydrophilic is reported, achieving the desired change in wettability for microporous as well as ultrafiltration polys sulfurone membranes, illustrating the universality of this method.
192 citations
TL;DR: This review addresses the recent research progress made to improve aqueous solubility, functionalization of biomolecules to QD surface and the poorly understood chemistry involved in the steps of bio-functionalization of such nanoparticles.
192 citations
TL;DR: A novel method of preparing hydrophobic silica particles by surface functionalization using different alkyltrichlorosilanes to generate hierarchical structures for selective adsorbents and catalysts, chromatographic supports and separators in microfluidic devices is described.
192 citations
15 Aug 2003
TL;DR: Gold nanoparticles prepared through a conventional citrate-reduction method were directly coated with silica by means of a seeded polymerization technique based on the Stöber method, and the optical spectra of the core-shell gold-silica composite particles agreed with predictions of Mie theory.
Abstract: Gold nanoparticles prepared through a conventional citrate-reduction method were directly coated with silica by means of a seeded polymerization technique based on the Stober method. The method required no surface modification. The addition of tetraethylorthosilicate and water prior to ammonia was found to be critical to obtain a proper coating. The silica shell thickness was varied from 30 to 90 nm for TEOS concentrations of 0.0005–0.02 M at 10.9 M of water and 0.4 M of ammonia. The optical spectra of the core–shell gold–silica composite particles agreed with predictions of Mie theory.
192 citations