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Surface plasmon resonance

About: Surface plasmon resonance is a research topic. Over the lifetime, 24909 publications have been published within this topic receiving 810976 citations. The topic is also known as: Surface plasmon resonance & SPR (technology).


Papers
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Journal ArticleDOI
TL;DR: It is shown that receptor-mediated aggregation of anti-EGFR hybrid nanoparticles allows selective destruction of highly proliferative cancer cells using a nanosecond pulsed laser at 700?nm wavelength, a significant shift from the peak absorbance of isolated hybrid nanoparticle at 532?nm.
Abstract: Nanoparticles which consist of a plasmonic layer and an iron oxide moiety could provide a promising platform for development of multimodal imaging and therapy approaches in future medicine. However, the feasibility of this platform has yet to be fully explored. In this study we demonstrated the use of gold-coated iron oxide hybrid nanoparticles for combined molecular specific MRI/optical imaging and photothermal therapy of cancer cells. The gold layer exhibits a surface plasmon resonance that provides optical contrast due to light scattering in the visible region and also presents a convenient surface for conjugating targeting moieties, while the iron oxide cores give strong T2 (spin?spin relaxation time) contrast. The strong optical absorption of the plasmonic gold layer also makes these nanoparticles a promising agent for photothermal therapy. We synthesized hybrid nanoparticles which specifically target epidermal growth factor receptor (EGFR), a common biomarker for many epithelial cancers. We demonstrated molecular specific MRI and optical imaging in MDA-MB-468 breast cancer cells. Furthermore, we showed that receptor-mediated aggregation of anti-EGFR hybrid nanoparticles allows selective destruction of highly proliferative cancer cells using a nanosecond pulsed laser at 700?nm wavelength, a significant shift from the peak absorbance of isolated hybrid nanoparticles at 532?nm.

180 citations

Journal ArticleDOI
TL;DR: The direct immobilization of anti-activated leukocyte cell adhesion molecule (anti-ALCAM) was carried out on the pCB(2)-catechol(2) modified surface, and results showed that the antibody-immobilized surface maintained its excellent ultra-low fouling properties.

179 citations

Journal ArticleDOI
01 Jun 2010-ACS Nano
TL;DR: The results show that Ni acts as a roughness-diminishing growth layer for the Ag film while at the same time maintaining and enhancing the plasmonic properties of the combined structures, pointing toward its use for low-loss plAsmonic devices and optical metamaterials applications.
Abstract: This paper reports an effective method to enhance the surface plasmon resonance (SPR) on Ag films by using a thin Ni seed layer assisted deposition. Ag films with a thickness of about 50 nm were deposited by electron beam evaporation above an ultrathin Ni seed layer of approximately 2 nm on both silicon and quartz substrates. The root-mean-square (rms) surface roughness and the correlation length have been reduced from >4 nm and 28 nm for a pure Ag film to approximately 1.3 and 19 nm for Ag/Ni films, respectively. Both experimental and simulation results show that the Ag/Ni films exhibit an enhanced SPR over the pure Ag film with a narrower full width at half-maximum. Ag films with a Ge seed layer have also been prepared under the same conditions. The surface roughness can be reduced to less than 0.7 nm, but narrowing of the SPR curve is not observed due to increased absorptive damping in the Ge seed layer. Our results show that Ni acts as a roughness-diminishing growth layer for the Ag film while at the same time maintaining and enhancing the plasmonic properties of the combined structures. This points toward its use for low-loss plasmonic devices and optical metamaterials applications.

178 citations

Journal ArticleDOI
TL;DR: Comparing photoelectron emission intensity and dark-field scattering spectra of the same individual nanostars reveals differences in terms of observable plasmon resonance wavelengths and field enhancements.
Abstract: Plasmonic hotspots in single gold nanostars are located at the tips and can be excited selectively by laser light as evidenced by photoelectron emission microscopy. Selectivity is achieved through wavelength and polarization of the excitation light. Comparing photoelectron emission intensity and dark-field scattering spectra of the same individual nanostars reveals differences in terms of observable plasmon resonance wavelengths and field enhancements. Differences are explained with the underlying near- and far-field processes of the two techniques.

178 citations

Journal ArticleDOI
TL;DR: In this paper, the authors found that the maximum sensitivity is obtained for a silver layer about 55 nm thick in direct contact with the species to be quantified, corresponding to ca. 10−10 mol1−1 antibody.

178 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
20231,320
20222,684
20211,240
20201,422
20191,498
20181,528