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Temporal cortex

About: Temporal cortex is a research topic. Over the lifetime, 8318 publications have been published within this topic receiving 597857 citations.


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Journal ArticleDOI
28 Sep 2001-Science
TL;DR: The functional architecture of the object vision pathway in the human brain was investigated using functional magnetic resonance imaging to measure patterns of response in ventral temporal cortex while subjects viewed faces, cats, five categories of man-made objects, and nonsense pictures, and a distinct pattern of response was found for each stimulus category.
Abstract: The functional architecture of the object vision pathway in the human brain was investigated using functional magnetic resonance imaging to measure patterns of response in ventral temporal cortex while subjects viewed faces, cats, five categories of man-made objects, and nonsense pictures. A distinct pattern of response was found for each stimulus category. The distinctiveness of the response to a given category was not due simply to the regions that responded maximally to that category, because the category being viewed also could be identified on the basis of the pattern of response when those regions were excluded from the analysis. Patterns of response that discriminated among all categories were found even within cortical regions that responded maximally to only one category. These results indicate that the representations of faces and objects in ventral temporal cortex are widely distributed and overlapping.

3,763 citations

Journal ArticleDOI
23 Aug 1985-Science
TL;DR: The filtering of irrelevant information from the receptive fields of extrastriate neurons may underlie the ability to identify and remember the properties of a particular object out of the many that may be represented on the retina.
Abstract: Single cells were recorded in the visual cortex of monkeys trained to attend to stimuli at one location in the visual field and ignore stimuli at another. When both locations were within the receptive field of a cell in prestriate area V4 or the inferior temporal cortex, the response to the unattended stimulus was dramatically reduced. Cells in the striate cortex were unaffected by attention. The filtering of irrelevant information from the receptive fields of extrastriate neurons may underlie the ability to identify and remember the properties of a particular object out of the many that may be represented on the retina.

2,671 citations

Journal ArticleDOI
TL;DR: In this paper, the authors present longitudinal measures of five-year change in the regional brain volumes in healthy adults and assess the average and individual differences in volume changes and the effects of age, sex and hypertension with latent difference score modeling.
Abstract: Brain aging research relies mostly on cross-sectional studies, which infer true changes from age differences. We present longitudinal measures of five-year change in the regional brain volumes in healthy adults. Average and individual differences in volume changes and the effects of age, sex and hypertension were assessed with latent difference score modeling. The caudate, the cerebellum, the hippocampus and the association cortices shrunk substantially. There was minimal change in the entorhinal and none in the primary visual cortex. Longitudinal measures of shrinkage exceeded cross-sectional estimates. All regions except the inferior parietal lobule showed individual differences in change. Shrinkage of the cerebellum decreased from young to middle adulthood, and increased from middle adulthood to old age. Shrinkage of the hippocampus, the entorhinal cortices, the inferior temporal cortex and the prefrontal white matter increased with age. Moreover, shrinkage in the hippocampus and the cerebellum accelerated with age. In the hippocampus, both linear and quadratic trends in incremental age-related shrinkage were limited to the hypertensive participants. Individual differences in shrinkage correlated across some regions, suggesting common causes. No sex differences in age trends except for the caudate were observed. We found no evidence of neuroprotective effects of larger brain size or educational attainment.

2,635 citations

Book
01 Sep 1992
TL;DR: The Nature of Sch schizophrenia, Behavioural Abnormalities in Schizophrenia, and Communication in Sch schizophrenia: Linking the Mind and the Brain are studied.
Abstract: Schizophrenic patients have bizarre experiences which reflect a disorder in the contents of consciousness. For example, patients hear voices talking about them or they are convinced that alien forces are controlling their actions. Their abnormal behaviour includes incoherence and lack of will. In this book an explanation of these baffling signs and symptoms is provided using the framework of cognitive neuropsychology.The cognitive abnormalities that underlie these signs and symptoms suggest impairment in a system which constructs and monitors representations of certain abstract (especially mental) events in consciousness. For example, schizophrenic patients can no longer construct representations of their intentions to act. Thus, if actions occur, these will be experienced as coming out of the blue and hence can seem alien. The patient who lacks awareness of his own intentions will stop acting spontaneously and hence will show a lack of will.The psychological processes that are abnormal in schizophrenia can be related to underlying brain systems using evidence from human and animal neuropsychology. Interactions between prefrontal cortex and other parts of the brain, especially temporal cortex appear critical for constructing the contents of consciousness. It is these interactions that are likely to be impaired in schizophrenia.

1,931 citations

Journal ArticleDOI
TL;DR: Because the MPFC and related limbic structures provide forebrain modulation over visceral control structures in the hypothalamus and brainstem, their dysfunction can account for the disturbances in autonomic regulation and neuroendocrine responses that are associated with mood disorders.
Abstract: The neural networks that putatively modulate aspects of normal emotional behavior have been implicated in the pathophysiology of mood disorders by converging evidence from neuroimaging, neuropathological and lesion analysis studies. These networks involve the medial prefrontal cortex (MPFC) and closely related areas in the medial and caudolateral orbital cortex (medial prefrontal network), amygdala, hippocampus, and ventromedial parts of the basal ganglia, where alterations in grey matter volume and neurophysiological activity are found in cases with recurrent depressive episodes. Such findings hold major implications for models of the neurocircuits that underlie depression. In particular evidence from lesion analysis studies suggests that the MPFC and related limbic and striato-pallido-thalamic structures organize emotional expression. The MPFC is part of a larger “default system” of cortical areas that include the dorsal PFC, mid- and posterior cingulate cortex, anterior temporal cortex, and entorhinal and parahippocampal cortex, which has been implicated in self-referential functions. Dysfunction within and between structures in this circuit may induce disturbances in emotional behavior and other cognitive aspects of depressive syndromes in humans. Further, because the MPFC and related limbic structures provide forebrain modulation over visceral control structures in the hypothalamus and brainstem, their dysfunction can account for the disturbances in autonomic regulation and neuroendocrine responses that are associated with mood disorders. This paper discusses these systems together with the neurochemical systems that impinge on them and form the basis for most pharmacological therapies.

1,921 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
202336
2022106
2021380
2020362
2019331
2018330