Topic
Terpene
About: Terpene is a research topic. Over the lifetime, 2208 publications have been published within this topic receiving 51480 citations. The topic is also known as: terpenes.
Papers published on a yearly basis
Papers
More filters
Patent•
18 Jul 1986
TL;DR: Novel terpene amino alcohols having an antiallergic activity or an activity of improving cerebral function are provided in this article, where medicinal uses of the alcohols are also discussed.
Abstract: Novel terpene amino alcohols having an antiallergic activity or an activity of improving cerebral function are provided Also provided are medicinal uses of the alcohols
28 citations
TL;DR: Four new terpenes were isolated from the methanolic extract prepared from the leaves of G. rhopalocarpa together with the known steroid stigmasterol and the coumarin, scopoletin and showed weak antiprotozoal activity against Leishmania donovani promastigotes, and Trypanosoma brucei brucesi blood stream trypomastigote.
28 citations
01 Jan 2005
TL;DR: The most common approach to drug penetration enhancement is the use of chemical agents which modify the skin barrier properties as discussed by the authors, and the following properties are desired1: It should be nontoxic, nonirritating, exhibit no pharmacological property of its own, exert reversible effects on the skin, and be cosmetically acceptable.
Abstract: Introduction 159
Structural Classification 160
Structure-Activity Relationships 162
Improving Permeation Enhancement Ability of Terpenes 163
Mechanism of Action of Terpenes 165
Terpene Derivatives as Enhancers 168
Conclusions 171
References 171One of the most common approaches to drug penetration enhancement is the use
of chemical agents which modify the skin barrier properties. For such an enhancer
to be acceptable, the following properties are desired1: It should be nontoxic, nonirritating, exhibit no pharmacological property of its own, exert reversible effects on the
skin, and be cosmetically acceptable. While a number of chemicals such as sulfoxides,
alcohols, pyrrolidones, fatty acids, Azone have been studied, none of them have been
proven to be outstanding often due to safety concerns. Terpenes may offer advantages
over such enhancers because of their natural origin as well as Generally Regarded As
Safe (GRAS) status. They are carbon, hydrogen, and oxygen containing nonaromatic
compounds found in essential oils, extracted from flowers, fruits, and other natural
products. These compounds have been used for a long time as fragrances and flavoring
agents in commercial preparations (sweets, toothpastes, cigarettes). Table 13.1 provides
examples of essential oils which have various terpenes or terpenoids as their main
constituents.
27 citations
TL;DR: This review summarizes recent research on terpenoids with regard to grape wine and discusses traits involved in wine aroma quality, and the strategies that can be used to improve grapevine breeding technology.
Abstract: Terpenes significantly affect the flavor and quality of grapes and wine. This review summarizes recent research on terpenoids with regard to grape wine. Although, the grapevine terpene synthase gene family is the largest identified, genetic modifications involving terpenes to improve wine flavor have received little attention. Key enzyme modulation alters metabolite production. Over the last decade, the heterologous manipulation of grape glycosidase has been used to alter terpenoids, and cytochrome P450s may affect terpene synthesis. Metabolic and genetic engineering can further modify terpenoid metabolism, while using transgenic grapevines (trait transfer to the plant) could yield more flavorful wine. We also discuss traits involved in wine aroma quality, and the strategies that can be used to improve grapevine breeding technology.
27 citations
TL;DR: Three cDNAs encoding putative terpene synthases from olive fruits of cv.
27 citations