Topic
Theobromine
About: Theobromine is a research topic. Over the lifetime, 1137 publications have been published within this topic receiving 29723 citations. The topic is also known as: 3,7-Dimethylxanthine & Theobromin.
Papers published on a yearly basis
Papers
More filters
TL;DR: In this article, the synthesis of theobromine is described as an experiment for the undergraduate organic chemistry laboratory and the N-methylation is monitored by TLC using authentic standards.
11 citations
TL;DR: These C8-(hydroxymethyl) Caffeine 12a-l, 13a-c and 14a-b have been found to show promising in vitro antioxidant as well as antiplatelet activities.
11 citations
TL;DR: In this article , the authors compared the roasted and non-roasted teas by liquid-chromatography mass spectrometry and sensory evaluation, and found that the roasted tea tasted less bitter and astringent.
11 citations
TL;DR: An optimized analytical method using liquid chromatography-tandem mass spectrometry (LC-MS/MS) for their detection in wastewater samples was developed in this study and the concentration of caffeine derivatives in wastewater influent is a tool for estimating the population size in the area served by WWTPs.
Abstract: For caffeine and its seven major metabolites (i.e., theobromine, theophylline, paraxanthine, 1-methylxanthine, 3-methylxanthine, 7-methylxanthine, and xanthine), an optimized analytical method using liquid chromatography-tandem mass spectrometry (LC-MS/MS) for their detection in wastewater samples was developed in this study. Extraction of these compounds (recoveries ranged from 60.3 to 83.2%) was made possible by combining universal polymeric reversed-phase cartridge and polymeric strong cation exchange cartridge. This method was applied to the determination of caffeine and its metabolites in the influent and effluent of an anaerobic-anoxic-oxic (A2O) process. In the A2O influent, caffeine and its metabolites (except xanthine) ranged from 1.39 to 5.45 μg/L, and their concentrations in the A2O effluent ranged from 10.2 to 171.3 ng/L. The mass load of caffeine was 14.9 g/day/1000 inhabitants, considering the population served by the target wastewater treatment plant (WWTP). The concentration of caffeine derivatives in wastewater influent is a tool for estimating the population size in the area served by WWTPs.
11 citations
TL;DR: In this article, the content of purine alkaloids in seeds of fourTheobroma species from the Amazon basin was analized by a reversed phase high-performance liquid chromatographic method.
Abstract: The content of purine alkaloids in seeds of fourTheobroma species from the Amazon basin was analized by a reversed phase high-performance liquid chromatographic method.Theobroma grandiflorum was found to contain 0.38% of 1,3,7,9-tetramethyluric acidT. subincanum 0.07% 1,3,7,9-tetramethyluric acid,T. speciosum 0.01% theobromine and 0.04% 1,3,7,9-tetramethyluric acid and finallyT. mariae 2.35% theobromine and 0.12% caffeine. Theophylline could not be detected in any of these species. The results were confirmed qualitatively by thin-layer chromatography.
11 citations