Topic
Toad
About: Toad is a research topic. Over the lifetime, 1624 publications have been published within this topic receiving 28732 citations.
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TL;DR: Aldosterone increases the sodium transport and the water-permeability response of the toad urinary bladder to antidiuretic hormone and to its intracellular mediator, c-AMP, while the activity of cyclic nucleotide phosphodiesterase is depressed.
4 citations
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TL;DR: It is suggested that Gpp(NH)p can enhance the physiological effect of vasopressin by stimulating vasoppressin activation of adenylate cyclase during substrate and hormone depletion of the toad bladder.
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TL;DR: The results suggest that calmodulin, colocalized with the calcium pump at the SC cytoplasmic level, would be involved in the active transport of the cation inside the secretory granules, maintaining adequate levels of intracellular Ca(2+) .
Abstract: The presence of a calcium pump, calbindin D-28KD, and calmodulin in the secretory cells (SC) of the oviductal pars convoluta (PC) of Rhinella arenarum was established for the first time in amphibians using immunohistochemical techniques Marked variations were observed in the localization and degree of expression of these proteins according to the duct segment and the period of the sexual cycle analyzed During the preovulatory and ovulatory periods the calcium pump colocalized with calbindin D-28KD can be seen mainly in the apical border of the SC, which are located in the first zones of PC and synthesize and secrete the components of the inner jelly coat layers These envelopes, which surround the oocytes, contain the molecules indispensable for fertilization, probably inducing the sperm acrosome reaction (AR) Our results suggest that calmodulin, colocalized with the calcium pump at the SC cytoplasmic level, would be involved in the active transport of the cation inside the secretory granules, maintaining adequate levels of intracellular Ca2+ During the postreproductive period, a calcium pump colocalized with calbindin D-28KD appears for the first time in the cycle in the basal zones of the SC This system may be related to the replenishing of intracellular Ca2+ stores In contrast, in R arenarum the Ca2+ present in the jelly coats that surround the oocytes participates in the AR during fertilization, suggesting that this secretion system of the cation provided by the oviductal mucosa is functionally more active during the reproductive period of this species J Exp Zool 321A: 432–441, 2014 © 2014 Wiley Periodicals, Inc
4 citations