Topic
Toad
About: Toad is a research topic. Over the lifetime, 1624 publications have been published within this topic receiving 28732 citations.
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TL;DR: Steady-state analysis of the acid extracts of the intermediate pituitary of the toad, Bufo marinus, revealed the presence of multiple forms of beta-endorphin and alpha-MSH, indicating that the N-acetylation ofbeta-endomorphin andalpha- MSH occurs at distinct subcellular sites in intermediate pituitsary cells of anuran amphibians.
20 citations
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TL;DR: Isotope incorporation in this fraction is increased after incubation of the tissue with aldosterone, which makes it possible to characterize a rapidly labelled RNA fraction which could, at least in part, represent messenger RNA.
20 citations
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20 citations
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TL;DR: Cholinomimetic drugs, anticholinesterases and ACh antagonists were applied topically on the isolated toad spinal cord and the effects on ventral root reflex responses and the polarization levels in dorsal and ventral roots were recorded.
20 citations
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TL;DR: It is suggested that a rise in cytosolic calcium is responsible for the inhibitory effect of quinidine on Na, H+, and water transport, and could not be elicited by an equivalent dose of tetracaine, suggesting that the inhibitor effect ofQuinidine is not dependent on its anesthetic properties.
Abstract: The effect of quinidine on Na and H+ transport by the turtle bladder and water transport by the toad bladder was examined. Quinidine inhibited the short-circuit current and the potential difference in a dose-dependent fashion. The effect of quinidine on the short-circuit was not dependent on extracellular calcium concentration and was not reversible with removal of the drug. Quinidine inhibited H+ secretion in a dose-dependent fashion. The effect of quinidine on H+ secretion also was not dependent on extracellular calcium concentration and was not reversible, either with removal of the drug or with stimulation of H+ secretion with 5% CO2. The effect of quinidine on Na or H+ transport could not be elicited by an equivalent dose of tetracaine, suggesting that the inhibitory effect of quinidine is not dependent on its anesthetic properties. Quinidine also inhibited vasopressin and cyclic AMP stimulated water flow in the toad bladder. Quinidine did not alter calcium uptake by the turtle bladder but increased calcium efflux by the turtle and toad bladders. These observations suggest that a rise in cytosolic calcium is responsible for the inhibitory effect of quinidine on Na, H+, and water transport.
19 citations