Showing papers on "Transcription factor published in 1976"
TL;DR: It is suggested that the mode of action of two transcription factors previously isolated from lentil root nuclei increase the number and/or the stability of the initiation complexes.
3 citations
01 Jan 1976
TL;DR: The chick oviduct progesterone receptor has been purified to homogeneity by affinity chromatography and its molecular action studied in vitro and the study suggests a novel model for homone action that can be tested directly in this system.
Abstract: The chick oviduct progesterone receptor has been purified to homogeneity by affinity chromatography and its molecular action studied in vitro. The native receptor is a 200,000 MW dimer of two dissimilar 4S subunits with different intranuclear function. The receptors directly regulate RNA chain initiation sites in oviduct chromatin by interactions involving target tissue nuclear acceptor sites. There is a 1:1 correspondence between receptor "acceptor" sites and RNA sites. Only the dimer form of the receptor is active in vitro on chromatin templates. The study suggests a novel model for homone action that can be tested directly in this system.
3 citations