Topic
Triazene
About: Triazene is a research topic. Over the lifetime, 759 publications have been published within this topic receiving 8714 citations. The topic is also known as: Triazene cleavage & 1-triazene.
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TL;DR: In this paper, the development of novel multi-substituted aryl-phosphonate compounds offers promise as new building blocks for metal-organic frameworks (MOFs) materials with excellent properties in regards to por...
Abstract: The development of novel multi-substituted aryl-phosphonate compounds offers promise as new building blocks for metal-organic frameworks (MOFs) materials with excellent properties in regards to por...
2 citations
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TL;DR: The UV–Vis spectroscopic results indicate also that triazene salts tends to interact with negatively charged DNA phosphate chain.
Abstract: Synthesis, characterization and investigation of antiproliferative activity of nine triazene salts against human cancer cells lines (MV-4-11, MCF-7, JURKAT, HT-29, Hep-G2, HeLa, Du-145 and DAUDI), and normal human mammary epithelial cell line (MCF7-10A) is presented. The structures of novel compounds were determined using 1H and 13C NMR, and GC-APCI-MS analyses. Among the derivatives, compound 2c, 2d, 2e and 2f has very strong activity against biphenotypic B myelomonocytic leukemia MV4-11, with IC50 values from 5.42 to 7.69 µg/ml. The cytotoxic activity of compounds 2c-2f against normal human mammary gland epithelial cells MCF-10A is 6–11 times lower than against cancer cell lines. Our results also show that compounds 2c and 2f have very strong activity against DAUDI and HT-29 with IC50 4.91 µg/ml and 5.59 µg/ml, respectively. Their lipophilicity was determined using reversed-phase ultra-performance liquid chromatography and correlated with antiproliferative activity. Our UV–Vis spectroscopic results indicate also that triazene salts tends to interact with negatively charged DNA phosphate chain. To support the experiment, theoretical calculations of the 1H NMR shifts were carried out within the Density Functional Theory.
2 citations
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21 Jul 1994TL;DR: The organosilicon compounds can be employed as thermo- and photolabile free-radical initiators for the preparation of homopolymers and block copolymers from olefinically unsaturated compounds.
Abstract: The organosilicon compounds contain at least one Si-C bonded organic radical containing at least one triazene group. The organosilicon compounds can be employed as thermo- and photolabile free-radical initiators for the preparation of homopolymers, graft copolymers and block copolymers from olefinically unsaturated compounds and for the crosslinking of organosilicon compounds and free-radical-polymerisable organic compounds.
2 citations
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28 Nov 1987
TL;DR: A triazene derivative of formula I (X is halogen; Y is lower alkyl, lower alkoxyl or OH; R is lower alkynyl) can be produced by diazotizing the aniline derivative of the formula II and reacting the obtained diazonium salt with the secondary amine of formula III as discussed by the authors.
Abstract: NEW MATERIAL:A triazene derivative of formula I (X is halogen; Y is lower alkyl, lower alkoxyl or OH; R is lower alkynyl) EXAMPLE:1,1-Dimethyl-3-(3-chloro-4,5-dipropargyloxyphenyl)triazene USE:An agricultural and horticultural fungicide It exhibits strong selective fungicidal effect against phytopathogenic fungus and other mold resistant to cyclic imide fungicides PREPARATION:The compound of formula I can be produced by diazotizing the aniline derivative of formula II and reacting the obtained diazonium salt with the secondary amine of formula III
2 citations