Topic
Triazene
About: Triazene is a research topic. Over the lifetime, 759 publications have been published within this topic receiving 8714 citations. The topic is also known as: Triazene cleavage & 1-triazene.
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01 Jan 2015
TL;DR: The study has brought about a novel application of this class of analytical reagents as an emerging class of bioactive chemicals.
Abstract: Antibacterial activities of four hydroxytriazenes namely 3-hydroxy-3-m-chlorophenyl-1-(4sulphonamidophenyl)triazene, 3-hydroxy-3-n-propyl-1-(4-sulphonamidophenyl)triazene, 3-hydroxy-3-isopropyl-1(4-sulphonamidophenyl) triazene, and 3-hydroxy-3-m-tolyl-1-p-chlorophenyltriazene and their ternary complexes with vanadium (V) using thiourea as second ligand have been screened against four bacterial strains viz.: Pseudomonas aeruginosa, Proteus mirabilis, Klebsiella pneumoniae and Escherichia coli at 100 and 200 ppm. Thus the study has brought about a novel application of this class of analytical reagents as an emerging class of bioactive chemicals.
2 citations
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10 Sep 1973TL;DR: In this article, a meso-ionic para-halophenyl substituted triazolines were used to inhibit plant growth by contacting a plant or its growth area with an effective amount of certain triazoline substituted with benzenediazoniumchloride and alpha-amino carboxylic acid.
Abstract: A process for inhibiting plant growth comprising contacting a plant or its growth area with an effective amount of certain para-halophenyl substituted triazolines. A series of novel mesoionic para-halophenyl substituted triazolines. A novel process for preparing 3-phenyl-4-oxo-1,2,3-triazoline by contacting benzenediazoniumchloride and an alpha -amino carboxylic acid and cyclodehydrating the triazene produced using acetic anhydride and pyridine.
2 citations
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TL;DR: In this article, N-phenyl-4-cyano-1-azabuta-1,3-diene and N-substituted-pyrrol-2-yl)-3-tosyltriazene are produced by reaction of the corresponding 2-lithiopyrroles with tosyl azide and successive reaction of lithium triazene salts with======tetraalkylammonium bromide.
Abstract: N-Methyl- and
N-phenyl-4-cyano-1-azabuta-1,3-diene (1a and 1b
respectively) are produced by vacuum–thermal fragmentation
and ring cleavage of
1-(N-substituted-pyrrol-2-yl)-3-tosyltriazene
tetraalkylammonium salts, prepared by reaction of the
corresponding 2-lithiopyrroles with tosyl azide and successive
reaction of the resulting lithium triazene salts with
tetraalkylammonium bromide.
2 citations
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TL;DR: In this paper, the hydrosoluble triazene derivatives of phenylacetic, phenylbutyric and cinnamic acid have been synthesized and their logP and pKa values were simultaneously determined according to a multiparametric fitting of potentiometric data.
Abstract: The hydrosoluble triazene derivatives of phenylacetic, phenylbutyric and cinnamic acid have been synthesized and their logP and pKa values were simultaneously determined according to a multiparametric fitting of potentiometric data. The antitumor activity caused by the synthesized compounds in mice bearing either Lewis lung carcinoma or TLX5 lymphoma was evaluated and discussed in comparison with the parent compound (p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt (DM-COOK, CAS 70055-49-1). The tested compounds were at least as active as DM-COOK, the cinnamic and the phenylacetic derivatives being the more active compounds in mice bearing TLX5 lymphoma and Lewis lung carcinoma, respectively.
2 citations
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TL;DR: Preliminary data on the hydrolysis of 1,3-di(p-carboxyphenyl)triazene dipotassium salt seem to indicate the essential role of alkylcarbo cation in mediating the antitumor action of aryldimethyltriazenes.
Abstract: The aim of this study is to investigate the hydrolysis of 1,3-di(p-carboxyphenyl)triazene dipotassium salt, AVIS (1), over a pH range of 2.60-8.50. This compound decomposes into p-aminobenzoic acid and the corresponding diazonium cation with no formation of alkylcarbo cations; the same compounds are formed from hydrolyses of DM-COOK (2), an antimetastatic agent, and of its possible demethylated metabolite, MM-COOK (3), a chemical xenogenization inducer. In these latter cases, however, a methylcarbo cation is formed. The pH dependence of the pseudo-first-order rate constants is intermediate between 2 and 3. Preliminary data on its toxicity and antitumor activity on both Lewis lung carcinoma and TLX5 lymphoma seem to indicate the essential role of alkylcarbo cation in mediating the antitumor action of aryldimethyltriazenes.
2 citations