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Triazene

About: Triazene is a research topic. Over the lifetime, 759 publications have been published within this topic receiving 8714 citations. The topic is also known as: Triazene cleavage & 1-triazene.


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Journal ArticleDOI
TL;DR: Triazene formation was partly inhibited in the presence of vegetable juice, and there was a high positive correlation between the nitrite concentration in the saliva and the triazene yield.

1 citations

Journal ArticleDOI
TL;DR: Its structural characterization by X-ray analysis and 1H NMR spectroscopy is performed to determine molecular overall conformation in view of its possible interaction to DNA.
Abstract: Biologically active 4-nitro-substituted 1,3-diaryltriazene, a chemical analogue of 1,3- bis (4'-amidinophenyl)-triazene-berenil ® , belongs to the novel, chemically modified class of potent antitumor agents. Its structural characterization by X-ray analysis and 1 H NMR spectroscopy is performed to determine molecular overall conformation in view of its possible interaction to DNA

1 citations

Journal ArticleDOI
TL;DR: Aldol addition of α-triisopropylsilyl-α-diazoacetone, promoted by excess lithium diisopropylamide (LDA), was developed and applied to the synthesis of original C-TIPS diazoaldols, C- TIPS diazoketols, and a related Mannich-type product as discussed by the authors.
Abstract: Aldol addition of α-triisopropylsilyl-α-diazoacetone (TIPS-diazoacetone), promoted by excess lithium diisopropylamide (LDA), was developed and applied to the synthesis of original C-TIPS diazoaldols, C-TIPS diazoketols, and a related Mannich-type product. An unprecedented mechanistic pathway has been proposed, involving a lithiated triazene intermediate resulting from the nucleophilic addition of LDA on the diazo moiety, supported by experimental results and DFT calculations.

1 citations

Journal ArticleDOI
TL;DR: In this paper , the synthesis of a terminal 1-alkynyl triazene was described, which allows the preparation of a range of functional groups including esters, alcohols, cyanides, phosphonates, and amides.
Abstract: 1-Alkynyl triazenes are versatile reagents in synthetic organic chemistry, but the structural diversity of this compound class has so far been limited. Herein, we describe the synthesis of a terminal 1-alkynyl triazene. Subsequent functionalization allows the preparation of 1-alkynyl triazenes with a range of functional groups including esters, alcohols, cyanides, phosphonates, and amides. Furthermore, the terminal 1-alkynyl triazene can be used for the synthesis of di- and triynes and for the preparation of (hetero)aromatic triazenes in metal-catalyzed cyclization reactions.

1 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
20236
202223
202116
202015
201917
201813