Topic
Trigonella
About: Trigonella is a research topic. Over the lifetime, 2274 publications have been published within this topic receiving 32361 citations.
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TL;DR: The present findings indicate that the SDF fraction of T. foenum-graecum seeds exerts antidiabetic effects mediated through inhibition of carbohydrate digestion and absorption, and enhancement of peripheral insulin action.
Abstract: Trigonella foenum-graecum (fenugreek) seeds have been documented as a traditional plant treatment for diabetes. In the present study, the antidiabetic properties of a soluble dietary fibre (SDF) fraction of T. foenum-graecum were evaluated. Administration of SDF fraction (0 x 5 g/kg body weight) to normal, type 1 or type 2 diabetic rats significantly improved oral glucose tolerance. Total remaining unabsorbed sucrose in the gastrointestinal tract of non-diabetic and type 2 diabetic rats, following oral sucrose loading (2 x 5 g/kg body weight) was significantly increased by T. foenum-graecum (0 x 5 g/kg body weight). The SDF fraction suppressed the elevation of blood glucose after oral sucrose ingestion in both non-diabetic and type 2 diabetic rats. Intestinal disaccharidase activity and glucose absorption were decreased and gastrointestinal motility increased by the SDF fraction. Daily oral administration of SDF to type 2 diabetic rats for 28 d decreased serum glucose, increased liver glycogen content and enhanced total antioxidant status. Serum insulin and insulin secretion were not affected by the SDF fraction. Glucose transport in 3T3-L1 adipocytes and insulin action were increased by T. foenum-graecum. The present findings indicate that the SDF fraction of T. foenum-graecum seeds exerts antidiabetic effects mediated through inhibition of carbohydrate digestion and absorption, and enhancement of peripheral insulin action.
250 citations
22 Aug 2002
TL;DR: An in-depth review on the Genus Trigonella and particularly the species T. foenum-graecum L. (fenugreek) is presented and will be of interest to all those concerned with the study, cultivation and use of medicinal and aromatic plants and particularly of fenugreek.
Abstract: Fenugreek presents an in-depth review on the Genus Trigonella and particularly the species T foenum-graecum L (fenugreek) It is written by experts and includes chapters describing the genus' botany, physiology, cultivation, breeding, nutrition, pest-disease and weed control The chemical constituents of the species of Trigonella, their pharmacological properties and the marketing of fenugreek seed are also discussed as are its medicinal applications A detailed presentation of the usefulness of fenugreek seed as food (whole, flour, roasted), spice (in curry powder), perfume, dye and source of galactomannan and steroidal diosgenin, widely used in industry, is also included The book will be of interest to all those concerned with the study, cultivation and use of medicinal and aromatic plants and particularly of fenugreek
222 citations
Journal Article•
TL;DR: Fenugreek may have a potential benefit in the treatment of non-insulin dependent diabetics (NIDDM) and had no effect on lipid levels 3 h following the MTT.
Abstract: The effect of fenugreek on postprandial glucose and insulin levels following the meal tolerance test (MTT) was studied in non-insulin dependent diabetics (NIDDM). The addition of powdered fenugreek seed (15 g) soaked in water significantly reduced the subsequent postprandial glucose levels. The plasma insulin also tended to be lower in NIDDM given fenugreek but without a statistical difference. Fenugreek had no effect on lipid levels 3 h following the MTT. Fenugreek may have a potential benefit in the treatment of NIDDM.
208 citations
TL;DR: The results suggest that the aqueous extract of Trigonella foenum-graecum leaves given both orally and intraperitoneally possesses a hypoglycaemic effect in normoglycaemia and alloxan induced hyperglycaemic rats.
208 citations
TL;DR: In this article, ground beef patties (75% lean) containing synthetic antioxidants, or Fenugreek (Trigonella foenumgraecum) extracts were cooked to internal temperature 70°C, and evaluated for storage stability at 4°C.
Abstract: Ground beef patties (75% lean) containing synthetic antioxidants, or Fenugreek (Trigonella foenumgraecum) extracts were cooked to internal temperature 70°C, and evaluated for storage stability at 4°C. Thiobarbituric acid values of raw or cooked samples containing fenugreek extracts were lower than controls (P<0.05). Fenugreek extracts delayed the induction period of oxidative rancidity. No differences were observed in psychrotrophic bacterial counts, and samples containing fenugreek extracts had lower Hunterlab “a” and higher “b” values. Samples with Fenugreek extracts had better oxidative stability and Fenugreek may be a promising natural antioxidant source.
197 citations