Showing papers on "Triterpene published in 1988"
TL;DR: Six triterpenes were isolated from Paeonia japonica tissue culture and determined by spectral methods to be oleanolic acid, hederagenin, betulinic acid, 24-cycloartanol, 30-norhederagenin and 23-hydroxybetulinic Acid.
101 citations
TL;DR: Findings suggest that the absence of glycyrrhizin in undifferentiated cultured cells may be partly due to interruption of the later reactions leading to the synthesis of glyCyrrhiza glabra from a triterpenoid intermediate.
Abstract: Callus and cell suspension cultures of Glycyrrhiza glabra failed to produce detectable amounts of glycyrrhizin, the major oleanane-type triterpene glycoside of the thickening root, or of its 11 —deoxoderivative. However, betulinic acid, a lupane-type triterpene, which was found in the root bark, and a small amount of β-amyrin, a possible precursor of oleanane-type triterpenes, were detected in cell suspension cultures in addition to lupeol, a fundamental form of lupane-type triterpenes. These findings suggest that the absence of glycyrrhizin in undifferentiated cultured cells may be partly due to interruption of the later reactions leading to the synthesis of glycyrrhizin from a triterpenoid intermediate.
91 citations
TL;DR: Hyptatic acid-A and 2α-hydroxyursolic acid demonstrated significant in vitro cytotoxicity in human colon HCT-8 tumour cells in this paper, using Spectral data in conjunction with X-ray analysis of the methanol solvate of hyptasis capitata.
81 citations
TL;DR: In this article, two triterpenoids were isolated together with β-amyrin acetate, taraxeryl acetate and lupenyl acetate from the whole herb of Euphorbia maculata.
63 citations
TL;DR: A new diosphenol-type triterpene fupenzic acid, was isolated from the fruits of Rubus chingii and characterized as 2,19α-dihydroxy-3-oxo-urs-1,12-dien-28-oic acid on the basis of UV, MS, 1 H and 13 C NMR spectral analysis as well as chemical conversion.
56 citations
TL;DR: A triterpene glycoside, quinovic acid-3β-O -β- d -glucopyranosyl-(27→1)-β-D - glucopyranoyl ester, and two known glycosides were isolated from the roots of Guettarda platypoda.
51 citations
TL;DR: Besides triterpenes and bergenin, ent-3β-hydroxykaur-16-ene and two oleanadienols were isolated from the stem bark of Phyllanthus flexuosus.
50 citations
TL;DR: In this paper, three new lanostanoid triterpenes, isolated from the mycelia of the fungus Ganoderma lucidum, were determined to be 3β-hydroxy-15α-acetoxy-lanosta-7,9(11),24-trien-26-oic acid, 3βα-acctoxy-15 α-hydroxyl-15-hydro-lanostanoxyl-lanossa-7 and 3α-oxo-15a-acetoxylacetoxy -lanosta
48 citations
TL;DR: In this article, four new triterpenes, isolated from the mycelia of the fungus Ganoderma lucidum, were determined to be lanosta-7,9(11),24-trien-3α, 15α-dihydroxy-26-oic acid, lanosta 7,9,11,12,14,15,16,17,18,19,20,21,22,22β-diacetoxy-3β-hydroxyl-26 oic acid.
47 citations
TL;DR: In vitro structure-activity studies suggested that triterpenoid glycosides which were originally used as herbal drugs and folk remedies in many areas of the world, were in fact inhibitory compounds, thus explaining the EBV activation in the in vitro test system.
44 citations
TL;DR: Five new triterpenes were isolated together with the known triterpene diol, betulin, from the stem bark of Phyllanthus flexuosus on the basis of spectroscopic evidence.
TL;DR: In addition to four triterpenes previously found, 12 triterps were isolated from the whole herb of Euphorbia supina along with sitosterol as mentioned in this paper, including fernane, simiarane and multiflorane skeletons.
TL;DR: The oleoresin of Aucoumea klaineana yielded nine triterpenes, six based on the tirucallane and three on the oleanane series.
TL;DR: In this article, two new diarylheptanoid glycosides (1 and 2) were isolated together with vanillic acid and six known triterpenoids, maslinic acid, alphitolic acid, arjunolic acid and oleanolic acid acetate, from the stem bark of Myrica rubra SIEB.
Abstract: Two new diarylheptanoid glycosides (1 and 2) were isolated together with vanillic acid and six known triterpenoids, maslinic acid, alphitolic acid, arjunolic acid, myricolal, oleanolic acid and oleanolic acid acetate, from the stem bark of Myrica rubra SIEB. et ZUCC. (Myricaceae). On the basis of spectral and chemical evidence, the structures of 1 and 2 were established as myricanol 5-O-β-D-(6'-O-galloyo)-glucopyranoside and myricanol 5-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside, respectively.
TL;DR: In this paper, six tetracyclic triterpenes based on the tirucallane/euphane skeleton have been isolated from the fruits of Phellodendron chinense.
TL;DR: A new triterpene was isolated from the methanol extracts of Akebia quinata tissue culture and the structure was determined by spectra and chemical transformations to be 3α,24-dihydroxy-30-norolean-12,20(29)-dien-28-oic acid.
TL;DR: A new 1α-hydroxy pentacyclic triterpenoid acid, imberbic acid, has been isolated from the leaves of Combretum imberbe and its structure established as 1α,3β-dihydroxyolean-12-en-29-oic acid by chemical and spectral analysis as mentioned in this paper.
TL;DR: In this paper, triterpene glucosides have been isolated from methanol extract of the leaves of Aphloia theiformis and the identities of the compounds were established by spectroscopic (1 H NMR, 13 C NMR and MS) and chemical methods (hydrolysis, acetylation).
TL;DR: Treatment of suspension cultures of some Tabernaemontana species (Apocynaceae) with elicitors result in a rapid de novo production of antimicrobial active triterpenes, identified as ursene carboxylic acid derivatives.
Abstract: Treatment of suspension cultures of some Tabernaemontana species (Apocynaceae) with elicitors (e.g. cellulase, Candida albicans) result in a rapid de novo production of antimicrobial active triterpenes. The triterpenes are identified as ursene carboxylic acid derivatives. These triterpenes are not produced by an elicited cell suspension culture of Catharanthus roseus, another Apocynaceae.
TL;DR: The abundance of this triterpene suggests that it may be a taxonomical marker of the seeds of Cucurbitaceae since only a few higher plants are known to contain isomultiflorenol.
Abstract: Compositions of the triterpene alcohol fractions of the unsaponifiable lipids obtained from 28 seed and mature plant [aerial parts (leaves and stems), pericarp of the fruits, and roots] of 13 genera of the family Cucurbitaceae were determined by gas liquid chromatography (GLC) on an OV-17 glass capillary column. Among the 14 tetracyclic and pentacyclic triterpene alcohols identified, isomultiflorenol was found to be the major component for most of the seed materials. The abundance of this triterpene suggests that it may be a taxonomical marker of the seeds of Cucurbitaceae since only a few higher plants are known to contain isomultiflorenol. The mature plant materials of the Cucurbitaceae, on the other hand, were shown to contain either one or some of the common triterpene alcohols such asα- andβ-amyrins, cycloartenol and 24-methylenecycloartanol as the major triterpene constituents.
TL;DR: In this article, five triterpene galactosides, pouosides A-E, have been isolated from a Pacific marine sponge, Asteropus sp. Structures were determined from spectroscopic data, especially extensive 1 H and 13 C NMR data and 2D NMR experiments.
Abstract: Five new triterpene galactosides, pouosides A-E, have been isolated from a Pacific marine sponge, Asteropus sp. The carbon skeleton of the pouoside aglycons is new for naturally occurring triterpenes and parallels that of the C 40 carotenoids. Structures were determined from spectroscopic data, especially extensive 1 H and 13 C NMR data and 2D NMR experiments. A novel saponin in which amino sugars are incorporated was isolated from the same sponge. Pouoside A, 1, is cytotoxic
TL;DR: Four triterpene saponins have been isolated, separated and purified from the roots of black medick trefoil and the biological significance of the presence of these compounds is discussed.
Abstract: Four triterpene saponins have been isolated, separated and purified from the roots of black medick trefoil. These have been identified as soyasaponin 1, hederagenin 3-O-β-D-glucopyranoside, medicagenic acid 3-O-β-D-glucopyranoside and medicagenic acid 3,28-di(O-β-D-glucopyranoside). The biological significance of the presence of these compounds is discussed.
TL;DR: A 3,28-bidesmosidic triterpenoid saponin, foetidissimoside A, was isolated from the roots of Cucurbita foetiissima and its structure established as echinocystic acid 3- O -β- d -glucuropyranoside 28- O −[β-d -xylopyranosyl (1 → 44)α- l -rhamnopyraniumyl(1 → 2)]-α-l -arabinopyrano-
TL;DR: In this article, triterpenoid glycosides from the aerial parts of Corchorus acutangulus were identified as saikogenin C, 3- O -β-d -glucopyranosyl (1 → 2)-β- d -galactopyranoide (6 ) based on their spectroscopic properties and some chemical transformations.
TL;DR: Two monoterpene glycosides isolated from the stem of Berchemia racemosa, have been characterized as (+)-angelicoidenol-2- O -β- d -glucopyranoside and (−)-angelica-nol 2- O −β-d -glocopyranoide on the basis of chemical and spectral evidence as discussed by the authors.
TL;DR: The resin obtained from Commiphora incisa has yielded two novel triterpenes which have been identified as 1α-acetoxy-9,19-cyclolanost-24-en-3 β-ol and 29-norlanost-8,24-dien-1α,2α,3β-triol, which appear to originate from the closely related C. kua.
TL;DR: A new pentacyclic triterpene acid has been isolated from the stem bark of Myrianthus arboreus and its structure has been established as 3β,6β-dihydroxyolean-12-en-29-oic acid and named myrianthinic acid.