Showing papers on "Triterpene published in 1991"
TL;DR: Two new friedelane-type triterpenes, named as cangoronine and ilicifoline respectively, have been isolated from Maytenus Ilicifolia by spectroscopic and X-ray analyses and the cytotoxic activities of these compounds are reported.
87 citations
TL;DR: The effects of the constituent sesquiterpene glycosides 1-3 and polyhydroxylated triterpenoids 5-6 isolated by MeOH extraction of Eriobotrya japonica were studied in genetically diabetic mice and normoglycemic rats.
Abstract: The effects of the constituent sesquiterpene glycosides 1-3 and polyhydroxylated triterpenoids 5-6 isolated by MeOH extraction of Eriobotrya japonica were studied in genetically diabetic mice (C57BL/KS-db/db/Ola) and normoglycemic rats. The sesquiterpene glycoside 3 and the polyhydroxylated triterpenoids 5 and 6 produced a marked inhibition of glycosuria. Furthermore, 5 and 6 were able to reduce blood glucose levels in normoglycemic rats. While there are already some data reported on hypoglycemic activity of polyhydroxylated triterpenoids, there are no previous data showing hypoglycemic activity of sesquiterpene glycosides.
85 citations
TL;DR: In this paper, triterpene glycosides (holothurinosides A, B, C and D; 1,2,3 and 5 respectively) and desholothuranin A (4 ) have been isolated from the sea cucumber Holothuria forskalii.
64 citations
TL;DR: A compilation of the triterpenoid saponins isolated during the period from 1987 to mid-1989, together with their occurrence, available physical data and spectroscopy used for their characterization is included.
64 citations
TL;DR: In this paper, six antineoplastic isomalabaricane-type triterpenes, stelliferins A-F, were isolated from the Okinawan marine sponge Jaspis stellififera.
56 citations
TL;DR: The first total synthesis of triterpene ether teurilene using two vanadium-(V)-catalyzed oxidation-cyclization reactions with different stereoselectivities was reported in this paper.
Abstract: The first total synthesis of the triterpene ether teurilene has been accomplished utilizing two vanadium-(V)-catalyzed oxidation-cyclization reactions with different stereoselectivities. The synthesis involved stereoselective and step-by-step construction of 2,5-cis- and 2,5-trans-tetrahydrofuran rings, vanadium (V)-catalyzed oxidation of 4-substituted 4-en-1-ol and subsequent cyclization of the resulting anti-epoxy alcohol, and a similar oxidation-cyclization of 5-substituted 4-en-1-ol by way of syn-epoxy alcohol. An improved synthesis of 1, which featured direct formation of bis(tetrahydrofuran) from squalene derivative by simultaneous double oxidation-cyclization, was also accomplished
49 citations
TL;DR: Five known serratene triterpenes, a nor -serratenone and four new serratenes derivatives have been isolated from the bark of Pinus armandii.
45 citations
TL;DR: Four novel polyoxygenated lanostanoid triterpenes, named applanoxidic acids A, B, C, and D, have been isolated from an Indonesian tropical fungus, Ganoderma applanatum.
39 citations
TL;DR: From the acid fraction of the hexane extract of the needles of Abies marocana, three endoperoxide diterpenoids, methyl 12α-hydroxyabietate and a triterpenoid, in addition to other resin acids have been isolated as discussed by the authors.
38 citations
TL;DR: In this article, the structure of a new cytotoxic squalene-type triterpene, named eurylene, from Eurycoma longifolia was elucidated by spectroscopic data, chemical evidence and X-ray analysis.
37 citations
TL;DR: In addition to 3-epi-betulinic acid, three triterpene glycosides were isolated from leaves of Schefflera octophylla and the last two compounds were found for the first time in the plant kingdom.
TL;DR: Methanolic extracts of the stalks of Mucuna birdwoodiana on acid hydrolysis and subsequent methylation with diazomethane provided four triterpene sapogenols and investigation of glycosides after methylation of the same extract led to the isolation of four trities.
TL;DR: From the root bark of Cassine transvaalensis, a new peltogynoid, (+)-11,11-dimethyl-1,3,8,10-tetrahydroxy-9-methoxypeltogynan was obtained along with three pentacyclic triterpenes, canophyllol,canophyllal and 6β-hydroxy-lup-20(30)-en-3-one as discussed by the authors.
TL;DR: A new 3,28-bidesmosidic triterpenoid saponin was isolated from the leaves of Schefflera octophylla together with a new trisaccharide and oleanonic acid.
TL;DR: In this paper, from the ethanolic extract of the heartwood of Cedrela odorata, gedunin, 3β- O -β- d -glucopyranosyl-24-methyllenecholesterol, oleanonic acid, sitosterol, n -octacosanol and a new triterpene threo -23,24,25,25-trihydroxytirucall-7-en-3-one.
TL;DR: Synthesis of optically pure bicyclic intermediates representing the A/B and D/E fragments required for an approach to isoarborinol is described in this article, where the authors show how to synthesize a 2-methylcyclohexane-13-dione and a 1-methylcyclopentane-1,3dione.
TL;DR: In this article, 12 pentacyclic triterpenes were isolated from the outer bark of river birch, Betula nigra, and 3β-acetoxyolean-11-oxo-12-ene-28-oic acid was isolated for the first time from a Betula species.
Abstract: Twelve pentacyclic triterpenes were isolated from the outer bark of river birch, Betula nigra. 3β-Acetoxyolean-11-oxo-12-ene-28-oic acid was isolated for the first time from a Betula species. 3β-Caffeatoxyolean-12-ene-28-oic acid has been spectrally characterized for the first time. 3β-Acetoxyolean-12-ene-28-oic acid and 3β-acetoxyolean-11-oxo-12-ene-28-oic acid have been demonstrated to be active as antifeedants for the Colorado potato beetle, Leptinotarsa decemlineata.
Agip1
TL;DR: In this paper, 24,28-dinor-18α-oleanane has been isolated from a petroleum and its structure established on the basis of ID and 2D NMR spectroscopy.
TL;DR: In this paper, four oleanane-type triterpene saponins, named buddlejasaponins I (1), II (2), III (3) and IV (4), were isolated from the aerial parts of Buddleja japonica HEMSL, together with a known saponin saikosaponin a (5).
Abstract: Four new oleanane-type triterpene saponins, named buddlejasaponins I (1), II (2), III (3) and IV (4) were isolated from the aerial parts of Buddleja japonica HEMSL., together with a known saponin saikosaponin a (5). Their structures were elucidated on the basis of the chemical and spectroscopic studies.
TL;DR: A new triterpene, 3β-hydroxy-26-nor-9,19-cyclolanost-23-en-25-one was isolated from the leaves of Garcinia mangostana and its structure elucidated by 1H NMR and mass spectral studies.
TL;DR: The structures of two novel acylated triterpenoid saponins were isolated from Bellis perennis are elucidated by means of high field 1D and 2D NMR spectroscopic methods without recourse to derivatization or comparison with previous data.
TL;DR: In this paper, a pyrocincholic acid 3β-O -β-6-deoxy-d -glucopyranoside-28- O -ββ-d-glucophyranoide was isolated from aerial parts of Isertia haenkeana.
TL;DR: In the etiolated seedling of Euphorbia lathyris L., three groups of triterpenoids were found, located at different sites, and the extracted triter penoids were purified by TLC and HPLC and identified by GC/MS.
TL;DR: Dried leaves of Schefflera octophylla afforded a new sulphated triterpene glycoside which was determined as 3-epi-betulinic acid 3-O-sulphate 28-O-[alpha-L-rhamnopyranosyl(1----4)-O-beta-D-glucopyranusyl (1----6)]-beta
TL;DR: The structure of a new triterpenoid saponin, hispidacin, has been elucidated as soyasapogenol B-3-O-alpha-L-rhamnopyranopyranoside by a combination of fast-atom bombardment mass spectrometry, 13C NMR spectroscopy, and some chemical transformations.
TL;DR: In this paper, tragopogonsaponins A-R were isolated from the roots of Tragopogaon porrifolius L. (Compositae) and their structures were determined on the basis of spectral and chemical evidence.
Abstract: Eighteen novel triterpenoid saponins, named tragopogonsaponins A-R, were isolated from the roots of Tragopogon porrifolius L. (Compositae). The structures of these saponins were determined on the basis of spectral and chemical evidence. Seventeen of the saponins contained phenyl propionic acid derivative as ester moiety. Their structures were elucidated as oleananae-type triterpene saponins which have echinocystic acid as the aglycone moiety.
TL;DR: In this article, two A-ring contracted triterpenes, musancropic acids A and B, having a new triterpene backbone, were isolated as their methyl esters from the rootwood of the African tree Musanga cecropioides.
TL;DR: In this paper, a new squalene-type triterpene with cytostatic activity, named as longilene peroxide, was isolated from the woods of Eurycoma longifolia.
Abstract: A new squalene-type triterpene with cytostatic activity, named as longilene peroxide, was isolated from the woods of Eurycoma longifolia. The solution and solid forms were elucidated by spectroscop...
TL;DR: In this paper, the absolute stereochemistry of hancokinol, hancolupenone and hexacosanoate triterpenes from Cynanchum hancokianum has been elucidated by means of spectroscopic [nuclear magnetic resonance (NMR), circular dichroism (CD)] analyses.
Abstract: The absolute stereochemistry of hancokinol, hancolupenone, hancolupenol, hancolupenol hexacosanoate, which are novel triterpenes, from Cynanchum hancokianum, has been elucidated by means of spectroscopic [nuclear magnetic resonance (NMR), circular dichroism (CD)] analyses.