Topic
Uca pugilator
About: Uca pugilator is a research topic. Over the lifetime, 376 publications have been published within this topic receiving 12303 citations.
Papers published on a yearly basis
Papers
More filters
01 Jun 1995-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: These results provide the first evidence for dopaminergic inhibition of testicular maturation in a crustacean.
24 citations
TL;DR: Lysergic acid diethylamide evokes strong concentration of the erythrophoric pigment in intact fiddler crabs, Uca pugilator, but does not evoke pigment concentration in the ERYthrophores of eyestalkless crabs or legs isolated from intact crabs.
24 citations
TL;DR: This pathway of tyrosine metabolism may be involved in the synthesis of the fiddler crab cuticle hardening agent because it is shown to be a constituent of the epidermis.
23 citations
TL;DR: The regenerated limbs of the crabs that survived ecdysis were found to have lesions in the form of black areas in which the cuticle was improperly developed, and the number of setae on limbs was reduced compared to the number on limbs that had regenerated in clean sea water.
23 citations
TL;DR: Property distinguish the action of these invertebrate collagenolytic enzymes from the metalloenzyme collagenases of mammals are broad substrate specificity, including both noncollagenous proteins and collagen types I-V; ability to cleave the native triple helix of collagen at multiple loci; reduced affinity or higher Km for collagen; and lower specific activity on collagen fibrils.
Abstract: The collagenolytic properties of a trypsin-like protease from the hepatopancreas of the fiddler crab Uca pugilator have been examined. All collagen types, I-V, were attacked by this enzyme. Types III and IV were degraded much more rapidly than types I, II, and V. Crab protease produced multiple cleavages in the triple helix of each collagen at 25 degrees C; only in the case of type III collagen, however, was a major cleavage observed at a 3/4:1/4 locus that corresponded to the region of collagen susceptibility to mammalian collagenase action. Additionally, both the affinity and the specific activity of the crab protease for native collagen were lower than those which characterize mammalian collagenase. The results of this study, in conjunction with a previous report on the collagenolytic activity of another serine protease from the fiddler crab [Welgus, H. G., Grant, G. A., Jeffrey, J. J., & Eisen, A. Z. (1982) Biochemistry 21, 5183], suggest that the following properties distinguish the action of these invertebrate collagenolytic enzymes from the metalloenzyme collagenases of mammals: (1) broad substrate specificity, including both noncollagenous proteins and collagen types I-V; (2) ability to cleave the native triple helix of collagen at multiple loci; (3) reduced affinity or higher Km for collagen; and (4) lower specific activity on collagen fibrils.
23 citations