Topic
Ultraviolet light
About: Ultraviolet light is a research topic. Over the lifetime, 49494 publications have been published within this topic receiving 843151 citations.
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07 Jun 1994
TL;DR: In this article, a fiber reinforced optical microcable comprised of a buffered optical waveguide coated with fiber reinforced, ultraviolet light cured resin over which is formed an ultraviolet light-cured resin overcoat.
Abstract: The invention provides a fiber reinforced optical microcable comprised of a buffered optical waveguide coated with a fiber reinforced protective sheath made of a fiber reinforced, ultraviolet light cured resin over which is formed an ultraviolet light cured resin overcoat. The protective sheath is manufactured by soaking reinforcing fibers in the UV curable resin, placing the wetted fibers around the buffered optical waveguide, feeding both the fibers and buffered optical waveguide through a die, and curing the resin with ultraviolet light. Then, an ultraviolet light cured resin is flow coated over the protective sheath and cured with ultraviolet light to complete the microcable.
178 citations
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TL;DR: Treatment with UV and US reduced the numbers of selected inoculated bacteria on lettuce and strawberries, which could be good alternatives to other traditional and commonly used technologies such as chlorine and hydrogen peroxide solutions for fresh produce industry.
178 citations
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TL;DR: Most cells are unaffected by relatively high concentrations of psoralen photochemistry in the absence of ultraviolet light, and the metabolites of the psoralens have thus far not created a problem.
Abstract: Psoralen photochemistry is specific for nucleic acids and is better understood at the molecular level than are all other methods of chemical modification of nucleic acids. These compounds are used both for in vivo structure analysis and for photochemotherapy since they easily penetrate both cells and virus particles. Apparently, natural selection has selected for membrane and virus penetrability during the evolution of these natural products. Most cells are unaffected by relatively high concentrations of psoralens in the absence of ultraviolet light, and the metabolites of the psoralens have thus far not created a problem. Finally, psoralens form both monoadduct and cross-links in nucleic acid helices, the yield of each being easily controlled by the conditions used during the photochemistry.
178 citations
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TL;DR: Ultraviolet light damages DNA by converting two adjacent thymines into a thymine dimer which is potentially mutagenic, carcinogenic, or lethal to the organism and is repaired in E. coli by nucleotide excision repair in humans.
Abstract: Ultraviolet light damages DNA by converting two adjacent thymines into a thymine dimer which is potentially mutagenic, carcinogenic, or lethal to the organism. This damage is repaired by photolyase and the nucleotide excision repair system in E. coli by nucleotide excision repair in humans. The work leading to these results is presented by Aziz Sancar in his Nobel Lecture.
178 citations
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TL;DR: Prevention of ultraviolet photolysis of folate and other light sensitive nutrients by dark skin may be sufficient explanation for the maintenance of this characteristic in human groups indigenous to regions of intense solar radiation.
Abstract: Human populations native to areas of intense sunlight tend to be heavily melanized. Previous explanations for this relationship have invoked only weak selective pressures. To test the hypothesis that dark pigmentation may protect against photolysis of crucial light-sensitive vitamins and metabolites by ultraviolet light, folate was used as a model. It was found that exposure of human plasma in vitro to simulated strong sunlight causes 30 to 50 percent loss of folate within 60 minutes. Furthermore, light-skinned patients exposed to ultraviolet light for dermatologic disorders have abnormally low serum folate concentrations, suggesting that photolysis may also occur in vivo. Deficiency of folate, which occurs in many marginally nourished populations, causes severe anemia, fetal wastage, frank infertility, and maternal mortality. Prevention of ultraviolet photolysis of folate and other light sensitive nutrients by dark skin may be sufficient explanation for the maintenance of this characteristic in human groups indigenous to regions of intense solar radiation.
178 citations