Showing papers on "Vascular endothelial growth factor A published in 1960"
TL;DR: Sera of the guinea pig contain the inactive precursor of a globulin permeability factor activable by dilution in saline (PF/Dil) or by chemical fractionation, and the obvious hypothesis—that activation in injury is induced by contact of the pro-PF with damaged tissue—was investigated.
Abstract: THE sera of the guinea pig1,2, rat3, rabbit3and man4contain the inactive precursor (pro-PF) of a globulin permeability factor (PF) activable by dilution in saline (PF/Dil) or by chemical fractionation. The in vivomechanism of activation is unknown; but an obvious hypothesis—that activation in injury is induced by contact of the pro-PFwith damaged tissue—was investigated by testing the effect on guinea pig serum of debris from homogenates of guinea pig tissues.
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