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Water environment
About: Water environment is a research topic. Over the lifetime, 13384 publications have been published within this topic receiving 125138 citations.
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TL;DR: Compared with the other adsorbents, the as-prepared adsorbent had an excellent tetracycline adsorption capacity, and was expected to be widely applied in the advertisersorption treatment of tetrACYcline wastewater.
131 citations
TL;DR: In this paper, the two-dimensional mapping of dynamic viscoelastic functions for a polystyrene/pol(methyl vinyl ether) solid surface is successfully obtained by forced oscillation atomic force microscopy.
Abstract: It is shown that the two-dimensional mapping of dynamic viscoelastic functions for a polystyrene/pol(methyl vinyl ether) solid surface is successfully obtained by forced oscillation atomic force microscopy. The two dimensional resolution of the viscoelastic image is less than 100 nm. The method can be carried out in an air or water environment without any pretreatment
130 citations
TL;DR: The results suggest that the D3 structural models obtained from this study may be useful for the discovery and design of novel and potent D3 ligands and may be more effective for lead discovery from a large chemical database than either pharmacophore-based or structure-based database screening alone.
Abstract: The dopamine 3 (D3) subtype receptor has been implicated in several neurological conditions, and potent and selective D3 ligands may have therapeutic potential for the treatment of drug addiction, Parkinson's disease, and schizophrenia. In this paper, we report computational homology modeling of the D3 receptor based upon the high-resolution X-ray structure of rhodopsin, extensive structural refinement in the presence of explicit lipid bilayer and water environment, and validation of the refined D3 structural models using experimental data. We further describe the development, validation, and application of a hybrid computational screening approach for the discovery of several classes of novel and potent D3 ligands. This computational approach employs stepwise pharmacophore and structure-based searching of a large three-dimensional chemical database for the identification of potential D3 ligands. The obtained hits are then subjected to structural novelty screening, and the most promising compounds are tes...
129 citations
TL;DR: In this article, magnetic carbon-αFe/Fe3C derived from metal-organic frameworks (MOFs) were synthesized by a carbonization method and used for TCN adsorption.
128 citations
TL;DR: Chip-based biosensor arrays for label-free and high-throughput detection were fabricated and tested and achieved detection sensitivity up to 668 nm per refractive index unit, about 1.7 times larger than that reported on an array of nanoholes.
Abstract: Chip-based biosensor arrays for label-free and high-throughput detection were fabricated and tested. The sensor array was composed of a 150-nm-thick, 50-nm-gap, and 600-nm-period gold nanoslits. Each array size was 100 mumx100 mum. A transverse-magnetic polarized wave in these metallic nanostructures generated resonant surface plasmons at a wavelength of about 800 nm in a water environment. Using the resonant wavelength shift in the nanoslit array, we achieved detection sensitivity up to 668 nm per refractive index unit, about 1.7 times larger than that reported on an array of nanoholes. An antigen-antibody interaction experiment in an aqueous environment verified the sensitivity in a surface binding event.
127 citations