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Topic

Web application

About: Web application is a(n) research topic. Over the lifetime, 36094 publication(s) have been published within this topic receiving 434789 citation(s). The topic is also known as: web app & web-based application.

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Papers
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Open accessJournal ArticleDOI: 10.1093/BIOINFORMATICS/BTI770
15 Jan 2006-Bioinformatics
Abstract: Motivation: Homology models of proteins are of great interest for planning and analysing biological experiments when no experimental three-dimensional structures are available. Building homology models requires specialized programs and up-to-date sequence and structural databases. Integrating all required tools, programs and databases into a single web-based workspace facilitates access to homology modelling from a computer with web connection without the need of downloading and installing large program packages and databases. Results: SWISS-MODEL workspace is a web-based integrated service dedicated to protein structure homology modelling. It assists and guides the user in building protein homology models at different levels of complexity. A personal working environment is provided for each user where several modelling projects can be carried out in parallel. Protein sequence and structure databases necessary for modelling are accessible from the workspace and are updated in regular intervals. Tools for template selection, model building and structure quality evaluation can be invoked from within the workspace. Workflow and usage of the workspace are illustrated by modelling human Cyclin A1 and human Transmembrane Protease 3. Availability: The SWISS-MODEL workspace can be accessed freely at http://swissmodel.expasy.org/workspace/ Contact: Torsten.Schwede@unibas.ch Supplementary information: Supplementary data are available at Bioinformatics online.

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Topics: Workspace (56%), Web application (50%)

6,822 Citations


Open accessJournal ArticleDOI: 10.1016/S1473-3099(20)30120-1
Ensheng Dong1, Hongru Du1, Lauren Gardner1Institutions (1)
Abstract: The outbreak of the 2019 novel coronavirus disease (COVID-19) has induced a considerable degree of fear, emotional stress and anxiety among individuals around t

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Topics: Dashboard (business) (62%), Web application (53%)

5,397 Citations


Journal ArticleDOI: 10.1002/JCC.20945
Abstract: CHARMM is an academic research program used widely for macromolecular mechanics and dynamics with versatile analysis and manipulation tools of atomic coordinates and dynamics trajectories. CHARMM-GUI, http://www.charmm-gui.org, has been developed to provide a web-based graphical user interface to generate various input files and molecular systems to facilitate and standardize the usage of common and advanced simulation techniques in CHARMM. The web environment provides an ideal platform to build and validate a molecular model system in an interactive fashion such that, if a problem is found through visual inspection, one can go back to the previous setup and regenerate the whole system again. In this article, we describe the currently available functional modules of CHARMM-GUI Input Generator that form a basis for the advanced simulation techniques. Future directions of the CHARMM-GUI development project are also discussed briefly together with other features in the CHARMM-GUI website, such as Archive and Movie Gallery.

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2,976 Citations


Open accessJournal ArticleDOI: 10.1002/0471142727.MB1910S89
Abstract: High-throughput data production has revolutionized molecular biology. However, massive increases in data generation capacity require analysis approaches that are more sophisticated, and often very computationally intensive. Thus, making sense of high-throughput data requires informatics support. Galaxy (http://galaxyproject.org) is a software system that provides this support through a framework that gives experimentalists simple interfaces to powerful tools, while automatically managing the computational details. Galaxy is distributed both as a publicly available Web service, which provides tools for the analysis of genomic, comparative genomic, and functional genomic data, or a downloadable package that can be deployed in individual laboratories. Either way, it allows experimentalists without informatics or programming expertise to perform complex large-scale analysis with just a Web browser.

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Topics: Web service (55%), Web application (53%)

1,452 Citations


Open access
01 Jan 2007-
Abstract: Despite this, Web interaction designers can’t help but feel a little envious of our colleagues who create desktop software. Desktop applications have a richness and responsiveness that has seemed out of reach on the Web. The same simplicity that enabled the Web’s rapid proliferation also creates a gap between the experiences we can provide and the experiences users can get from a desktop application.

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Topics: Web modeling (78%), Ajax (75%), Web application (72%) ...read more

1,377 Citations


Performance
Metrics
No. of papers in the topic in previous years
YearPapers
202223
20211,052
20201,406
20191,550
20181,695
20171,692

Top Attributes

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Topic's top 5 most impactful authors

Gustavo Rossi

88 papers, 2.2K citations

Ali Mesbah

39 papers, 2K citations

Paolo Tonella

32 papers, 1.4K citations

Martin Gaedke

31 papers, 244 citations

Daniel Schwabe

27 papers, 786 citations

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