White Muscle Disease

About: White Muscle Disease is a research topic. Over the lifetime, 165 publications have been published within this topic receiving 2812 citations.

White muscle disease of sheep and associated tissue selenium levels in western australia

Abstract: White Muscle Disease of sheep occurs in Western Australia as distinct syndromes in lambs and weaner sheep. Mean liver selenium concentrations of lambs and weaners with WMD and unaffected by WMD were 0.19 and 0.46 ppm, and 0.20 and 0.41 ppm (dry weight) respectively. There was considerable overlap between levels suggesting that selenium status was not the only factor involved in the development of WMD.

Effects of selenium on animal health

Abstract: Selenium is an essential trace element in the diet of humans and domesticated animals. It is a component of more than 30 selenoproteins, which play a significant role in the body. Selenoproteins protect cells from damage inflicted by free radicals, the cause of many chronic diseases. They also participate in the metabolism of thyroid hormones, control reproductive functions and exert neuroprotective effects. In addition to its anti-proliferative and anti-inflammatory properties, selenium stimulates the immune system. The role of selenium is aided by vitamin E and sulfur-containing amino acids. Selenium deficiency contributes to pathological changes in farm animals, which incur large financial losses each year. Low selenium levels can lead to the development of nutritional muscular dystrophy, also known as white muscle disease, in lambs, kids, foals, calves and poultry from birth to 3 months of age. Selenium deficiency may also cause exudative diathesis in poultry as well as dietary necrotic liver degeneration and mulberry heart disease in pigs. Parturition problems resulting from reduced tension of the muscular layer of the uterus, postparturient paraplegia, placental retention and purulent inflammations of the uterine lining are also attributed to low selenium levels. Selenium deficiency contributes to the formation of ovarian cysts and increased embryonic mortality in the first 3-4 weeks after insemination. Selenium and vitamin E facilitate neutrophil migration to the mammary gland, and they enhance the bactericidal effects of neutrophils, thus shortening and alleviating the symptoms of clinical mastitis. Selenium poisoning is rarely encountered, and it most often results from an overdose of selenium supplements. The most common forms of selenosis are chronic selenosis, referred to as alkali disease, and acute selenosis, popularly known as blind staggers.