Showing papers on "Withania somnifera published in 1982"
01 Jan 1982
TL;DR: Withania somnifera, herbal rejuvenative tonic widely used by Ayurvedic physicians in India, was tested for its adaptogenic properties and appears to induce a state of non-specifically increased resistance (SNIR) during stress.
Abstract: Withania somnifera, herbal rejuvenative tonic widely used by Ayurvedic physicians in India, was tested for its adaptogenic properties. Pretreatment with this drug increased the swimming endurance in mice. It prevented gastric ulcers induced chemically or by stress in rats. Milk-induced leucocytosis was also prevented in mice. The drug prevented increase in adrenal weight and decrease in ascorbic acid and Cortisol content of adrenals during stress. It appears to induce a state of non-specifically increased resistance (SNIR) during stress.
83 citations
TL;DR: The structure of a new naturally occurring steroidal lactone of the withanolide group isolated from Withania somnifera chemotype III has been elucidated as (20 R,22 R )-14α,2Oα F -dihydroxy-1-oxowitha-2,5,16,24-tetraenolid.
30 citations
TL;DR: In this paper, Solasodine and 5,20α (R)-Dihydroxy-6α,7α-epoxy-1-oxo-(5a)-witha-2,24-dienolide and solasoda inhibit proliferation of murine spleen cell cultures.
Abstract: 5,20α (R)-Dihydroxy-6α,7α-epoxy-1-oxo-(5a)-witha-2,24-dienolide and solasodine inhibit proliferation of murine spleen cell cultures. The steroidal lactone occurs in the medicinal plants WITHANIA SOMNIFERA and LYCIUM CHINENSE. The steroidal alkaloid is contained inter alia in SOLANUM NIGRUM.
27 citations