Topic
Withania somnifera
About: Withania somnifera is a research topic. Over the lifetime, 2116 publications have been published within this topic receiving 43404 citations. The topic is also known as: Ashwaganda & Indian ginseng.
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TL;DR: Detailed chemical investigation of Withania somnifera roots resulted in the isolation and identification of a cytotoxic and hepatoprotective agent, palmitic acid, which was converted to eight semi-synthetic ester derivatives 2–9.
Abstract: Detailed chemical investigation of Withania somnifera roots resulted in the isolation and identification of a cytotoxic and hepatoprotective agent, palmitic acid (1), which was converted to eight s...
21 citations
TL;DR: The effect of carbon source and the initial medium pH on growth and production of withanolide A in adventitious root cultures of Withania somnifera was investigated and a 2% sucrose concentration was found to be best.
21 citations
TL;DR: The hedgehog (Hh) signaling pathway performs an important role in embryonic development and in cellular proliferation and differentiation, but aberrant activation of the Hh signaling pathway is associated with tumorigenesis and signal inhibition was evaluated using a cell-based assay system that targets GLI1-mediated transcription.
21 citations
01 Jan 2008
TL;DR: The present study was undertaken to study the effect of different extracts (agueous suspension, ether and water) of various parts of Withania somnifera (Solanaceae) against Callosobruchus chinensis L. chinensis, finding that a maximum of 63.33% adult mortality was observed in C.chinensis treated with 10% ether extracts of W. somNifera root.
Abstract: The present study was undertaken to study the effect of different extracts (agueous suspension, ether and water) of various parts of Withania somnifera (Solanaceae) against Callosobruchus chinensis L. A maximum of 63.33% adult mortality was observed in C.chinensis treated with 10% ether extracts of W. somnifera root.
21 citations
TL;DR: Red light and Violet light enhanced the total phenolic and flavonoid content in callus culture of W. somnifera with lower antioxidant enzymes activities and combination of thidiazuron and naphthalene acetic acid induced callus growth in Withania somNifera.
21 citations