Topic
Withania somnifera
About: Withania somnifera is a research topic. Over the lifetime, 2116 publications have been published within this topic receiving 43404 citations. The topic is also known as: Ashwaganda & Indian ginseng.
Papers published on a yearly basis
Papers
More filters
01 Jan 2017
TL;DR: Ethnobotanical and pharmacologic characteristics and therapeutic applications of the plant and its active constituents are recapitulate.
Abstract: Withania somnifera , also known as ashwagandha, is one of the prominent medicinal plants in Indian systems of medicine. Since antiquity, it is used against myriad of clinical conditions and, in fact, its history of use as a medicine dates back to AD 6000. The plant contains a range of different classes of chemical constituents such as alkaloids, steroidal lactones, and flavonoids. These chemical moieties are responsible for various biological activities of the plant. Laboratory studies demonstrated the plant to be antiinflammatory, antitumor, neuroprotective, antimicrobial, antistress, antidiabetic, and cardioprotective. These pharmacologic activities are in part due to the capability of W. somnifera to reduce reactive oxygen species, modulate mitochondrial function, regulate apoptosis, reduce inflammation, and enhance endothelial function. Additionally, it has been used singly or in combination against various diseases of humans. Here, we recapitulate ethnobotanical and pharmacologic characteristics and therapeutic applications of the plant and its active constituents.
15 citations
Journal Article•
TL;DR: The yield parameters and cost economics of Withania somnifera were studied using dual inoculation of Azotobacter chroococcum and Pseudomonas putida using a randomized block design.
Abstract: The yield parameters and cost economics of Withania somnifera were studied using dual inoculation of Azotobacter chroococcum and Pseudomonas putida. The experiment was conducted in a randomized block design with 3 replications for 2 consecutive years, along with 2 levels of organic manure, 10 t ha −1 and 20 t ha −1 . Inoculation with the
15 citations
TL;DR: WFA alleviated TDP-43 pathology while it boosted the levels of the autophagic marker LC3BII in the brain and reduced NF-κB activity and neuroinflammation in the head, suggesting that WFA and perhaps other autophagy inducers should be considered as potential therapy for neurodegenerative diseases with TDP
15 citations
TL;DR: In vitro study with W. somnifera root extracts was found to be effective against all the MDR S. aureus strains isolated from local and patient sources, and it may be concluded that the antimicrobials from W. Somersifera may raise an alternative therapy for MDR staphylococcal infections in near future.
15 citations
01 Jan 1987
15 citations