Withania somnifera

About: Withania somnifera is a research topic. Over the lifetime, 2116 publications have been published within this topic receiving 43404 citations. The topic is also known as: Ashwaganda & Indian ginseng.

Ameliorative effects of Withania somnifera, Azadirachta indica, Tinospora cordifolia and E care Se herbal preparations on chicken infectious anaemia virus induced haematological changes in chicks and their live body weights.

Abstract: The present study was performed to evaluate the potenƟ al of four herbal preparaƟons namely Withania somnifera, Tinospora cordifolia, Azadirachta indica and E Care Se Herbal against the haematological effects of chicken infecƟous anaemia virus (CIAV) in chicks and their live body weight gains Briefly, six experimental groups (A to F), containing fiŌeen chicks each, were treated with herbal pre paraƟons separately from day old age The chicks of Groups A to D were fed with W somnifera (1% pure extract), T cordifolia (1% pure extract), A indica (02% pure extract) and E Care Se Herbal (01% in drinking water), respecƟvely, while groups E and F were kept as virus posi‐ Ɵve and control grou p, respecƟvely Groups A to E were given infecƟon with 40 Ɵ mes 50% chicken infecƟous dose (CID50) of CIAV A strain intra‐ muscularly on 14th day of age Haematological parameters and body weight of the chicks of all the groups were recorded at weekly intervals for upto 10 weeks The chicks of herbal treatment groups (A‐D) showed significant im‐ provement in their mean body weight gain and haematological indices viz, packe d cell volume, haemoglobin level, total white blood cell, red blood cell and percentage lymphocyte counts, when compared with the virus infected group (E) In conclusion, the prophylacƟc/therapeuƟc applicaƟon of these herbal preparaƟons is suggested to combat depressed haematological pa‐ rameters and stunted growth in chi cks during CIAV infecƟon Further explor‐ aƟve studies would strengthen the potenƟal role of herbs against this eco‐ nomically important avian pathogen causing huge economic losses to poultry farmers 1 IntroducƟon

In vitro evaluation of total phenolics and antioxidant activities of withania somnifera, eclipta prostrata l and gossypium herbasceum l

Abstract: Traditional medicinal plant, Withania somnifera, Eclipta prostrata and Gossypium herbasceum were analyzed for reducing power ability as an antioxidant using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay and for total phenolics using the Folin-Ciocalteu method. The results of the analysis show that W. somnifera, E. prostrate and G. herbascium have percentage antioxidant activity (AA%) of 98.12±0.50, 96.45±0.45 and 90.62±0.35 respectively. W. somniferam and E. prostrate show higher while Gossypium herbasceum less activity than those of Gallic (92.92±0.55) and Ascorbic acids (94.81±0.56) used as standards. W. somnifera, E. prostrata and G. herbascium also show high reductive potential of 0.99, 0.94 and 0.90nm at the same concentration with Gallic acid whose reductive potential was 0.93nm. The total phenolic determination shows that W. somnifera, E. prostrate and G. herbascium have the phenolic content of 14, 12 and 11mg/g GAE respectively. The results of this analysis reveal the fact that plants are rich sources of natural antioxidant.

Antifungal and antibacterial activities of crude withanolides extract from the roots of Withania somnifera (L.) Dunal (Ashwagandha)

Abstract: Ashwagandha [Withania somnifera (L.) Dunal] is an important medicinal plant and its medicinal properties have been attributed to various classes of withanolide compounds. In the present study, we evaluated antifungal and antibacterial activities of withanolide extracted from roots of ashwagandha, against five pathogenic, fungi and bacteria. The minimal inhibitory concentration (MIC) of withanolides against two fungi, F. oxysporum and A. brassica were observed to be 4826.25 and 4474.22 ppm respectively. Antibacterial activity of withanolide extract was tested against three bacteria, E.