Withania somnifera

About: Withania somnifera is a research topic. Over the lifetime, 2116 publications have been published within this topic receiving 43404 citations. The topic is also known as: Ashwaganda & Indian ginseng.

Two withanolides from Withania somnifera (solanaceae) and activity of methanolic extracts against fungal and bacterial pathogens that affects food crops

Abstract: Methanolic extract obtained from the dried leaves of Withania Somnifera was subjected to column chromatography leading to the isolation of two withanolides. Their structures were elucidated using 1D and 2D NMR spectroscopy. The isolated withanolides were determined to be 5α, 17β-dihydroxy-6α, 7β-epoxy-1-oxo-witha-2, 24-dienolide (1) and 4, 5, 6, 15-tetrahydroxy-1-oxo-witha-7-enolide (2). The bioassay of the methanolic extracts showed activity against the fungal pathogens, Fusarium moniliforme, Fusarium graminearum, Colletotrichum lindemuthianum and Pythium spp. The extract was also active against bacterial pathogens, Xanthomonas campestris pv. phaseoli and Pseudomonas syringae pv. phaseolicola. The withanolides did not show any bioactivity indicating that they are either active only synergistically with other compounds within the extracts or there are other active compounds in the extract. Key words: Withania somnifera, withanolides, methanolic extract, antifungal, antibacterial.

Antibacterial activity of two medicinal plants: Withania somnifera and Curcuma longa

Abstract: In vitro aqueous and ethanol extracts of Withania somnifera (leaves and fruits) and Curcuma Longa were evaluated for antibacterial activities against Basillus subtillis, Staphylococcus aureus, Escherichia coli and S.epidermitis. The inorganic extract of W. somnifera leaves showed more antibacterial activity as compared to the organic fraction. While both the organic and inorganic phases of fruit extract of W. somnifera showed antibacterial activity against all the tested microorganisms. S.epidermitis and B.subtillis were inhibited by