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Withania somnifera

About: Withania somnifera is a research topic. Over the lifetime, 2116 publications have been published within this topic receiving 43404 citations. The topic is also known as: Ashwaganda & Indian ginseng.


Papers
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Patent
02 Dec 2013
TL;DR: In this paper, a combination of β-glucan and Withania somnifera synergistically increases the immune activity of the cytokines IL-12 and IL-6 over expected values.
Abstract: Compositions including combinations of β-glucan and Withania somnifera for increasing the immune activity of certain target cytokines and phagocytosis, and reducing cortisol or corticosterone. Methods of improving immunity activity under periods of stress including chronic stress with a combination of β-glucan and Withania somnifera are also described. Particular combinations of β-glucan and Withania somnifera synergistically increases the immune activity of the cytokines IL-12 and IL-6 over expected values.

2 citations

Journal ArticleDOI
TL;DR: This work presents a meta-analysis of data from eight African studies on the use of EMT in women with high-risk pregnancies to establish anaesthetised women’s response to EMT.
Abstract: No Abstract.The East and Central African Journal of Pharmaceutical Sciences Vol 8(1) 2005: 6-9

2 citations

Book ChapterDOI
01 Jan 2018
TL;DR: The present chapter provides a brief overview of challenges in W. somnifera and discusses some of the latest developments to address these challenges.
Abstract: Withania somnifera (L.) Dunal is one of the most reputed medicinal plants belonging to the family Solanaceae. The plant contains various steroidal lactones, alkaloids, polyphenols, flavanol glycosides, and sterols, which are responsible for its medicinal properties such as antitumor, neuroprotective, cardioprotective, antiaging, and anti-inflammatory. The main focus of research in W. somnifera is to increase the production of withanolides, the pharmaceutically important constituents. Various in vitro strategies like organ and cell culture and genetic manipulation and molecular biology tools such as metabolic engineering have been adapted to enhance secondary metabolite production. The present chapter provides a brief overview of challenges in W. somnifera and discusses some of the latest developments to address these challenges.

2 citations

Journal Article
TL;DR: It was concluded that synergized effects of light and alternating temperatures, enhanced seed germination of Hyoscyamus muticus and Solanum nigrum and the light regime can play a vital role in present and future weed management strategies.
Abstract: The objective of the present study was to evaluate the effects of nine combinations of temperature and light on seeds germination of four solanaceae species (Datura innoxia, Hyoscyamus muticus, Solanum nigrum and Withania somnifera) in germination chamber. The influence of combined of three alternative temperature regimes from 10 to 40 °C, with 10°C intervals, under three light levels (the continuous white light, alternative and darkness) were tested. The germination parameters as germination percentage, seed vigor index, dormancy, germination speed and germination index, and were measured and calculated. The data reveled some similarities in germination percentage and seedling vigor index among Datura innoxia, Solanum nigrum in one hand and between Hyoscyamus muticus and Withinia somnifera on the other hand, while germination speed and germination index showed some similarities between Datura innoxia, Withinia somnifera and between Hyoscyamus muticus and Solanum nigrum. The optimum condition for the germination of the seeds was varied with species (species-dependent): some species Hyoscyamus muticus and Withinia somnifera germinate easier under combined effects of light and temperature, whereas, Solanum nigrum and Datura innoxia decreased their germination in darkness conditions. The maximal germination was reached in Hyoscyamus muticus follwed by Withania somnifera, Solanum nigrum and Datura innoxia species under wide range of selected combinations. With the exception of Datura innoxia all other species seemed a photoplastic character. No relationship was found between germination percentage and alternating temperature especially in Hyoscyamus muticus and Withania somnifera. Alternating temperature is not the main factor affecting germination percentage. We concluded that the regime of light suppressed the effects alternating temperatures on seed germination of Datura innoxia species. It was concluded that synergized effects of light and alternating temperatures, enhanced seed germination of Hyoscyamus muticus and Solanum nigrum. Thus, the light regime can play a vital role in present and future weed management strategies.

2 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
2023114
2022265
202188
2020124
201995
2018111