Topic
Withania somnifera
About: Withania somnifera is a research topic. Over the lifetime, 2116 publications have been published within this topic receiving 43404 citations. The topic is also known as: Ashwaganda & Indian ginseng.
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TL;DR: In this article , the authors investigated the adaptogenic effects of Ashwagandha root extract in domestic dogs (Canis familiaris) and found that the root extract was associated with significant improvements in stress-related signs.
1 citations
TL;DR: Roots of ashwagandha are having anti-aging property and are prescribed in medicines for hiccup, several female disorders, bronchitis, rheumatism, dropsy and stomach, lung inflammation and skin diseases.
Abstract: Ashwagandha or Asgandh (Withania somnifera L. Dunal.) popularly known as ‘Indian Ginseng’ belongs to the family Solanaceae. It is found in wild state in the Mediterranean region of North Africa. In India it is mainly cultivated in Mandsaur district of Madhya Pradesh, adjoining villages of Kota district of Rajasthan, Punjab and Karnataka. Ashwagandha roots and occasionally its leaf and seeds are used in ayurvedic and unani medicines preparations (Majumdar, 1955). The total alkaloid content of the Indian ashwagandha roots is reported to vary between 0.13 to 0.31 per cent. Apart from roots, alkaloids have also been reported in leaves and berries (Sreerekha et al., 2004). The roots are prescribed in medicines for hiccup, several female disorders, bronchitis, rheumatism, dropsy and stomach, lung inflammation and skin diseases. They are mostly used for curing general and sexual disabilities. Roots are having anti-aging property (Savitha et al., International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 7 Number 09 (2018) Journal homepage: http://www.ijcmas.com
1 citations
Journal Article•
TL;DR: Ashwagandha root powder was analyzed for its physical, functional, reconstitutional and proximate composition in this article, which showed that it is great source of nutraceuticals and phytochemicals such as Alkaloid, Flavonoid, Tanin, Saponin, Carbohydrates and Glycosides.
Abstract: Ashwagandha root having a tremendous importance in Ayurveda and medical system. Based on these phytochemical screenings were carried out for various extracts of ashwagandha root powder. The preliminary phytochemical screening showed the presence of various phytochemicals viz., Alkaloid, Flavonoid, Tanin, Saponin, Carbohydrates and Glycosides. Various efforts have been made to evaluate functional and reconstitute properties of powder. Further ashwagandha root powder was analyzed for its physical, functional, reconstitutional and for proximate composition. Our study shows that ashwagandha root powder is great source of nutraceuticals and phytochemicals.
1 citations
Journal Article•
TL;DR: This article acts as a quick reference for extracting the anti-angiogenic properties of the following selected medicinal plants Alliumsativum, Aloe vera, Anacardium occidentale Linn, Ardisia pyramidalis Persoon, Bidens pilosa Linn.
Abstract: There is an increasing demand for the herbal drug treatment of various ailments and many plant drugs fromAyurvedic systemare being explored globally. This article acts as a quick reference for extracting the anti-angiogenic properties of the following selected medicinal plants Alliumsativum, Aloe vera, Anacardium occidentale Linn, Ardisia pyramidalis (Cavanilles) Persoon, Bidens pilosa Linn., Boerhaavia diffusa, Bombax ceiba, Camellia sinensis, Clerodendrum serratum (spreng.), Coffea Arabica, Gardenia jasminoides, Glycyrrhiza glabra, Parkia speciosa, Salvia officinalis, Silybum marianum, Tillandsia recurvata L., Withania somnifera.
1 citations
TL;DR: The endophytes of W. somnifera can be a good source for AgNP synthesis and showed a significant antimicrobial activity against tested microorganisms, especially E. coli followed by S. aureus and P. aeruginosa.
Abstract: Objectives: The main aim is to elaborate a cost-effective and environmentally friendly synthesis of silver nanoparticles (AgNPs) by endophytic extracts isolated from Withania somnifera as a reducing and capping agent, which has proven antibacterial activity against Escherichia coli, Pseudomonas aeruginosa , Staphylococcus aureus , and Klebsiella sp. Methods: Characterization of AgNPs was carried out employing ultraviolet-visible spectrophotometry, scanning electron microscopy (SEM), and X-ray diffraction studies (XRD). Antibacterial activity of AgNPs was conducted by disc diffusion method antimitotic activity was also evaluated by determining mitotic index in Allium cepa root tips. Results: Ultraviolet-visible spectroscopy was given a peak at 400 nm confirmed the AgNPs. The images of the SEM have confirmed the formation of AgNPs with an average size of 40 nm. XRD results were remarkable in confirmation of synthesized AgNPs with distinct XRD peaks at 2θ values of 38, 44, 64, and 77 lattice planes were observed which indexed the facts of silver (111), (200), (220), and (311), respectively. The AgNPs showed effective antibacterial activity against tested microorganisms at 100 μg/discs concentrations. A significant mitotic index (22.8±1.4b and 26.9±0.9b) was observed in A. cepa root tips at 10 mg/ml, 5 mg/ml concentration, respectively. Conclusion: It can be concluded that the endophytes of W. somnifera can be a good source for AgNP synthesis and showed a significant antimicrobial activity against tested microorganisms, especially E. coli followed by S. aureus and P. aeruginosa. Suggestive results were found in antimitotic activity which one of screening methods for development of anticancer drugs. An important outcome of our study will be the extension of value-added products for the industries of biomedical and nanotechnology based.
1 citations