Topic
Withania somnifera
About: Withania somnifera is a research topic. Over the lifetime, 2116 publications have been published within this topic receiving 43404 citations. The topic is also known as: Ashwaganda & Indian ginseng.
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TL;DR: In this paper, the authors investigated the withanolides as an immune booster and anti-viral anti-malignancy agent and found that withania somnifera is widely used as a medicine.
Abstract: Traditionally, Withania somnifera is widely used as an immune booster, anti-viral, and for multiple medicinal purposes. The present study investigated the withanolides as an immune booster and anti...
40 citations
TL;DR: The structure of 1α,3β,20α F -trihydroxy-20 R,22 R -witha-5,24-dienolide, a new naturally occurring steroidal lactone of the withanolide g
40 citations
01 Jul 2004
TL;DR: Hairy roots of Withania somnifera and Solanum surattense Burm f can be grown and established in phytohormone free liquid MS medium and used as a promising source of secondary metabolites of medicinal significance.
Abstract: Withania somnifera (L) Dunal. and Solanum surattense Burm f., the two medicinally important members of family Solanaceae, were investigated for induction of hairy roots using soil borne bacterium, Agrobacterium rhizogenes. Explants like stem segments, hypocotyls and leaves with midrib were infected with the bacterium in vitro. In both plants, extensive hairy roots were induced from leaf explant containing midrib within 15 days of infection. These roots were then established on MS basal medium and their growth was observed to be independent of exogenous supply of phytohormones. The growth rate of transformed roots was 10-fold as compared to control. These roots can be grown and established in phytohormone free liquid MS medium and used as a promising source of secondary metabolites of medicinal significance.
40 citations
TL;DR: In this article, the authors investigated the potential for two herbs commonly found in India, Ashwagandha (Withania somnifera) and Brahmi (Bacopa monnieri), to enhance immune function.
40 citations
TL;DR: The transformations of the epoxide group in withanolides of the withaferin A type showed moderate reduction in their cytotoxicity whereas the almost inactive withanones have shown some improvements in their alcohol derivatives.
40 citations