Xanthene

About: Xanthene is a research topic. Over the lifetime, 2132 publications have been published within this topic receiving 34803 citations. The topic is also known as: Xanthene & dibenzo[a,e]pyran.

Abraham model correlations for describing dissolution of organic solutes and inorganic gases in dimethyl carbonate

Abstract: Experimental solubility data are reported for anthracene, biphenyl, benzil, benzoin, 1-chloroanthraquinone, phenothiazine, pyrene, salicylamide, thioxanthen-9-one, xanthene, benzoic acid, 4-tert-bu...

The Heaviest Bottleable Metallylone: Synthesis of a Monatomic, Zero‐Valent Lead Complex (“Plumbylone”)

Abstract: Abstract The elusive plumbylone {[SiII(Xant)SiII]Pb0} 3 stabilized by the bis(silylene)xanthene chelating ligand 1, [SiII(Xant)SiII=PhC(NtBu)2Si(Xant)Si(NtBu)2CPh], and its isolable carbonyl iron complex {[SiII(Xant)SiII]Pb0Fe(CO)4} 4 are reported. The compounds 3 and 4 were obtained stepwise via reduction of the lead(II) dibromide complex {[SiII(Xant)SiII]PbBr2} 2, prepared from the bis(silylene)xanthene 1 and PbBr2, employing potassium naphthalenide and K2Fe(CO)4, respectively. While the genuine plumbylone 3 is rather labile even at −60 °C, its Pb0→Fe(CO)4 complex 4 turned out to be relatively stable and bottleable. However, solutions of 4 decompose readily to elemental Pb and {[SiII(Xant)SiII]Fe(CO)3} 5 at 80 °C. Reaction of 4 with [Rh(CO)2Cl]2 leads to the formation of the unusual dimeric [(OC)2RhPb(Cl)Fe(CO)4] complex 6 with trimetallic Rh−Pb−Fe bonds. The molecular and electronic structures of 3 and 4 were established by Density Functional Theory (DFT) calculations.

Improving Brightness and Stability of Si-Rhodamine for Super-Resolution Imaging of Mitochondria in Living Cells.

Abstract: Photostable and bright organic dyes emitting in the near-infrared region are highly desirable for long-term dynamic bioimaging. Herein, we report a synthetic approach to build novel methoxy modified Si-rhodamine (SiRMO) dyes by introducing the methoxybenzene on the xanthene moiety. The brightness of SiRMO increased from 2300 M-1 cm-1 (SiRMO-0) to 49000 M-1 cm-1 (SiRMO-2) when the substituent 2,5-dimethoxybenzene was replaced with 2,6-dimethoxybenzene. Moreover, the stability of SiRMO-2 was significantly improved due to the steric hindrance protection of the two methoxy groups on the ninth carbon atom of the xanthene. After fast cellular uptake, the SiRMO dyes selectively stained the mitochondria with a low background in live cultured cells and primary neurons. The high brightness and stability of SiRMO-2 significantly improved the capability of monitoring mitochondria dynamic processes in living cells under super-resolution conditions. Moreover, with the fluorescence nanoscopy techniques, we observed the structure of mitochondrial cristae and mitochondria fission, fusion, and apoptosis with a high temporal resolution. Under two-photon illumination, SiRMO-2 showed also enhanced two-photon brightness and stability, which are important for imaging in thick tissue.