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Xanthene

About: Xanthene is a research topic. Over the lifetime, 2132 publications have been published within this topic receiving 34803 citations. The topic is also known as: Xanthene & dibenzo[a,e]pyran.


Papers
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Journal ArticleDOI
TL;DR: In the title compound, C27H26O4, each of the cyclohexenone rings adopts a half-chair conformation to allow the formation of two intramolecular O—H⋯O hydrogen bonds, which are typical of xanthene derivatives.
Abstract: In the title compound, C27H26O4, each of the cyclo­hexenone rings adopts a half-chair conformation. The dihedral angle between the two phenyl rings is 89.53 (5)°. The hy­droxy and carbonyl O atoms face each other and are orientated to allow the formation of two intra­molecular O—H⋯O hydrogen bonds, which are typical of xanthene derivatives.

3 citations

Patent
30 Mar 2017
TL;DR: In this paper, the present specification relates to a novel xanthene-based compound, a colorant composition containing the same, and a resin composition that contains the same xanthenes.
Abstract: The present specification relates to a novel xanthene-based compound, a colorant composition containing the same, and a resin composition containing the same.

3 citations

01 Jan 2014
TL;DR: In this article, the nitration of a hydroxyxanthene dye sulfonefluorescein was reported and the orange dyes were identified as 4,5-dinitro and (probably) 2,4,5,7-tetranitro sulfone fluoresceins.
Abstract: In this paper, the nitration of a hydroxyxanthene dye sulfonefluorescein is reported. The orange dyes thus obtained are identified as 4,5-dinitro and (probably) 2,4,5,7-tetranitro sulfonefluoresceins. The spectral and acid-base properties, interaction with lysozyme, and behavior in surfactant solutions are examined using visible spectroscopy, LDI-ToF, and MALDI-ToF. The xanthene moiety of the dyes is stable against protonation, whereas at high pH values created by NaOH, the rupture of the pyrone cycle readily occurs. Further nucleophilic attack on the central carbon atom results in formation of the carbinolic structure.

3 citations

Proceedings ArticleDOI
11 May 2018
TL;DR: Magnetic nanoparticle supported phosphotungstic acid (Fe3O4@SiO2-HPW) was applied as a highly efficient catalyst for the synthesis of 14H-dibenzoxanthene derivatives via condensation reaction of 2-naphthol and aryl aldehydes as mentioned in this paper.
Abstract: Magnetic nanoparticle supported phosphotungstic acid (Fe3O4@SiO2-HPW) was applied as a highly efficient catalyst for the synthesis of 14H-dibenzoxanthene derivatives via condensation reaction of 2-naphthol and aryl aldehydes. The catalyst was found highly efficient for the synthesis of xanthene derivatives under solvent free condition. The catalyst showed high activity and stability during the reaction and provided excellent yield of the corresponding products in short reaction time. All the synthesized compounds were characterized through FT-IR, 1H-NMR and 13C-NMR spectroscopic techniques. Furthermore, the catalyst is magnetically recoverable and can be reused several times without significant loss of its catalytic activity.

3 citations

Journal ArticleDOI
TL;DR: This unit describes the preparation of 5‐ and 6‐carboxy derivatives of the xanthene fluorescent dyes fluorescein, 4‐dimethylamino‐2‐hydroxy‐2′,4′(5′)‐dicarboxybenzophenones, and their conversion to non‐nucleoside phosphoramidite reagents suitable for oligonucleotide labeling.
Abstract: This unit describes the preparation of 5- and 6-carboxy derivatives of the xanthene fluorescent dyes fluorescein (FAM), 4',5'-dichloro-2',7'-dimethoxy-fluorescein (JOE), and tetramethylrhodamine (TAMRA) as individual isomers, and their conversion to non-nucleoside phosphoramidite reagents suitable for oligonucleotide labeling. The use of a cyclohexylcarbonyl (Chc) protecting group for blocking of phenolic hydroxyls facilitates the chromatographic separation of isomers of carboxy-FAM and carboxy-JOE as pentafluorophenyl esters. Acylation of 3-dimethylaminophenol with 1,2,4-benzenetricarboxylic anhydride gave a mixture of 4-dimethylamino-2-hydroxy-2',4'(5')-dicarboxybenzophenones, easily separable into individual compounds upon fractional crystallization. Individual isomeric benzophenones are precursors of 5- or 6-carboxytetramethylrhodamines. The dyes were converted into 6-aminohexanol- (JOE), 4-trans-aminocyclohexanol- (FAM and JOE), and hydroxyprolinol-based (TAMRA) phosphoramidite reagents.

3 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
202354
2022136
202182
202091
201986
201891