Xanthene

About: Xanthene is a research topic. Over the lifetime, 2132 publications have been published within this topic receiving 34803 citations. The topic is also known as: Xanthene & dibenzo[a,e]pyran.

An Efficient Solvent Free Synthesis of 1,8-Dioxo-octahydroxanthene Using p-Toluene Sulfonic Acid

Abstract: A simple and efficient method for the synthesis of 1,8-dioxo-octahydroxanthene by using p-toluenesulfonic acid as a catalyst under solvent free conditions is described, which involves cyclization of 2,2-arylmethylenebis(3-hydroxy-5,5-dimethyl-2-cyclohexene-1-one) that was obtained firstly by the reaction of dimedone with aromatic aldehydes in water as solvent and catalyst at room temperature. The experimental procedures in the two steps are very simple and the products are formed in excellent yields.

Asymmetrical si rhodamine and rhodol synthesis

Abstract: [Problem] To provide: a compound resulting from substituting with a silicon atom the oxygen atom at position 10 of a xanthene ring site of a rhodamine of which amino groups at position 3 and position 6 have an asymmetrical structure; a method for producing the compound; and a fluorescent probe that uses the compound. [Solution] The compound represented by general formula (I) or a salt thereof.

Effect of anchoring groups on electrochemical self-assembly of ZnO/xanthene dye hybrid thin films

Abstract: Three xanthene dyes with different anchoring groups, eosin Y (EY), dicarboxy-eosin Y (CEY) and sulfonated eosin Y (SEY) were employed to electrodeposit ZnO/dye hybrid thin films to study the effect of anchoring groups on the electrochemical self-assembly (ESA) of hybrid thin films The adsorption stabilities of the dyes in oxidized form were in the order, CEY >> EY > SEY, as evaluated by Langmuir isothermal adsorption experiments The reduction potential of dyes, the dependence on Zn(2+) concentration that reflects stabilities of complexes between reduced dyes and Zn(2+) ion, and the diffusion coefficients of dyes were determined by electrochemical measurements These properties of the dyes were considered as the key parameters to dominate ESA of hybrid thin films which were actually prepared with these dyes by potentiostatic electrolysis at -08 and -10 V (vs SCE) representing ESA with dyes in oxidized and reduced forms, respectively, and were analyzed for their chemical composition and structural features

A new near-infrared phosphorescent iridium(III) complex conjugated to a xanthene dye for mitochondria-targeted photodynamic therapy

Abstract: Iridium(iii) complexes are potent candidates for photodynamic therapy (PDT), but some key drawbacks still hamper clinical translation, such as poor operability in the phototherapeutic window, high dark toxicity, and low reactive oxygen species (ROS) production efficiency. In this work, a near-infrared phosphorescent Ir(iii) complex conjugated to a xanthene dye, NIR-Ir-XE, is reported with highly favourable properties for mitochondria-targeted imaging and cancer phototherapy. The generation of the triplet excited state of a xanthene moiety endows the NIR-Ir-XE to form singlet oxygen (1O2) for use as a photodynamic therapy agent after irradiation with visible light. Compared with the xanthene-free Ir(iii) counterpart (NIR-Ir-bpy), the xanthene-modified cyclometalated Ir(iii) photosensitizer NIR-Ir-XE exhibits higher 1O2 generation efficiency, negligible dark toxicity and a better therapeutic effect. Importantly, a clear correlation between cell death and intracellular generation of 1O2 derived from NIR-Ir-XE after light irradiation was demonstrated. The corresponding in vivo photo-antitumor performance was further demonstrated to be effective in tumor-bearing mice. The observed properties of NIR-Ir-XE qualify it as a promising PDT agent.